Skip to main content

Table 3 Left: Diagnostic accuracy of YKL40 (defined by Youden’s optimal cut-off point) in predicting 30-day mortality. Right: Spearman Rank Correlation between disease severity scores and baseline YKL-40

From: Associations between YKL-40 and markers of disease severity and death in patients with necrotizing soft-tissue infection

Accuracy Correlation
   Rho P
Sensitivity 0.61 (95% CI 0.41–0.78)    
Specificity 0.70 (95% CI 0.61–0.77) SAPS II 0.33  < 0.001
PPV 0.30 (95% CI 0.18–0.43) SOFA Score 0.48  < 0.001
NPV 0.89 (95% CI 0.82–0.95) Lactate 0.49  < 0.001
AUC-ROC 0.64 (95% CI 0.52–0.76) Creatinine 0.46  < 0.001
  1. Data are presented as fractions (95% Confidence Interval)
  2. AUC-ROC area under the receiver operating characteristics curve, CI confidence interval, NPV negative predictive value, PPV positive predictive value, SAPS II simplified acute physiology score II, SOFA Score sequential organ failure assessment score day 1