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Table 3 Left: Diagnostic accuracy of YKL40 (defined by Youden’s optimal cut-off point) in predicting 30-day mortality. Right: Spearman Rank Correlation between disease severity scores and baseline YKL-40

From: Associations between YKL-40 and markers of disease severity and death in patients with necrotizing soft-tissue infection

Accuracy

Correlation

  

Rho

P

Sensitivity

0.61 (95% CI 0.41–0.78)

   

Specificity

0.70 (95% CI 0.61–0.77)

SAPS II

0.33

 < 0.001

PPV

0.30 (95% CI 0.18–0.43)

SOFA Score

0.48

 < 0.001

NPV

0.89 (95% CI 0.82–0.95)

Lactate

0.49

 < 0.001

AUC-ROC

0.64 (95% CI 0.52–0.76)

Creatinine

0.46

 < 0.001

  1. Data are presented as fractions (95% Confidence Interval)
  2. AUC-ROC area under the receiver operating characteristics curve, CI confidence interval, NPV negative predictive value, PPV positive predictive value, SAPS II simplified acute physiology score II, SOFA Score sequential organ failure assessment score day 1