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Table 2 General distribution and outcome type of new cases of drug-resistant tuberculosis, according to characteristics of block II, Brazil, 2013 and 2014

From: Brazilian cohort study of risk factors associated with unsuccessful outcomes of drug resistant tuberculosis

 

Total (980 cases)

Success treatment

Lost to follow-up

Failure

Death

 

N

%

N

%

N

%

N

%

N

%

Block II

          

Cavitation

          

Yes

753

76.8

474

62.9

127

16.9

62

8.2

90

12.0

No

227

23.2

147

64.8

36

15.9

14

6.2

30

13.2

Bilateral disease

          

Yes

614

62.7

369

60.1

101

16.4

57

9.3

87

14.2

No

366

37.3

252

68.9

62

16.9

19

5.2

33

9.0

Resistance type

          

Primary

231

23.6

166

71.9

32

13.9

15

6.5

18

7.8

Acquired

749

76.4

455

60.7

131

17.5

61

8.1

102

13.6

Initial resistance pattern

          

MDR/RR

965

98.5

616

63.8

162

16.8

74

7.7

113

11.7

XDR

15

1.5

5

33.3

1

6.7

2

13.3

7

46.7

Initial scheme type

          

Individualized

873

89.1

558

63.9

142

16.3

66

7.6

107

12.3

Standardized

107

10.9

63

58.9

21

19.6

10

9.3

13

12.1

Fluoroquinolone treatment

          

Only used Lfx or Mfx

935

95.4

594

63.5

158

16.9

70

7.5

113

12.1

Only used Ofx

12

1.2

6

50.0

3

25.0

2

16.7

1

8.3

Used more than one fluorquinolone or did not use

33

3.4

21

63.6

2

6.1

4

12.1

6

18.2

Injectable drug treatment

          

Just used Am

242

24.7

151

62.4

41

16.9

17

7.0

33

13.6

Only used S

607

61.9

391

64.4

103

17.0

41

6.8

72

11.9

Only used Cm

49

5.0

30

61.2

10

20.4

5

10.2

4

8.2

Used more than one injectable or did not use

82

8.4

49

59.8

9

11.0

13

15.9

11

13.4

Total

980

100.0

621

63.4

163

16.6

76

7.8

120

12.2

  1. MDR multidrug resistant, RR resistant to rifampicin diagnosed by GeneXpert MTB/RIF® (RR), XDR extensively resistant, Lfx levofloxacin, Mfx moxifloxacin, Ofx ofloxacino, Am amikacin, S streptomycin, Cm capreomycin