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Table 2 Correlation between IL-18 and IL-18bp and clinical data in patients

From: IL-18 and IL-18 binding protein are related to disease severity and parasitemia during falciparum malaria

 

IL-18

IL-18bp

M

M + HIV

All

M

M + HIV

All

IL-18bp

0.42**

0.09

0.32**

qMalPCR

0.37**

0.25*

0.27**

0.41**

0.43**

0.42**

eGFR

− 0.42**

− 0.29*

− 0.34**

− 0.46**

− 0.34**

− 0.38**

Haemoglobin

− 0.07

− 0.22

− 0.22*

0.18

0.26*

0.12

Platelets

− 0.21

− 0.17

− 0.20*

− 0.51**

− 0.37**

− 0.46**

Neutrophils

− 0.13

− 0.30*

− 0.26*

0.23

− 0.07

0.03

Lymphocytes

0.10

0.32

0.25*

− 0.36*

0.01

− 0.12

WBC

0.29*

0.07

0.18

0.28*

0.03

0.14

vWF

0.46**

0.22

0.38**

0.38**

0.03

0.25**

Severity

0.07

0.30*

0.30**

0.15

0.11

0.18*

IL− 27

0.52**

0.13

0.30**

0.59**

0.44**

0.51**

  1. Not all data were available in all patients. qMalPCR, quantitative PCR of falciparum malaria in plasma; severity, disease severity according to WHO classification, see Methods; eGFR, estimated glomerular filtration rate; WBC, total white blood cell counts; vWF, von Willebrand factor. *Correlation is significant at the 0.05 level (2-tailed). **Correlation is significant at the 0.01 level (2-tailed)