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Table 2 Correlation between IL-18 and IL-18bp and clinical data in patients

From: IL-18 and IL-18 binding protein are related to disease severity and parasitemia during falciparum malaria

  IL-18 IL-18bp
M M + HIV All M M + HIV All
IL-18bp 0.42** 0.09 0.32**
qMalPCR 0.37** 0.25* 0.27** 0.41** 0.43** 0.42**
eGFR − 0.42** − 0.29* − 0.34** − 0.46** − 0.34** − 0.38**
Haemoglobin − 0.07 − 0.22 − 0.22* 0.18 0.26* 0.12
Platelets − 0.21 − 0.17 − 0.20* − 0.51** − 0.37** − 0.46**
Neutrophils − 0.13 − 0.30* − 0.26* 0.23 − 0.07 0.03
Lymphocytes 0.10 0.32 0.25* − 0.36* 0.01 − 0.12
WBC 0.29* 0.07 0.18 0.28* 0.03 0.14
vWF 0.46** 0.22 0.38** 0.38** 0.03 0.25**
Severity 0.07 0.30* 0.30** 0.15 0.11 0.18*
IL− 27 0.52** 0.13 0.30** 0.59** 0.44** 0.51**
  1. Not all data were available in all patients. qMalPCR, quantitative PCR of falciparum malaria in plasma; severity, disease severity according to WHO classification, see Methods; eGFR, estimated glomerular filtration rate; WBC, total white blood cell counts; vWF, von Willebrand factor. *Correlation is significant at the 0.05 level (2-tailed). **Correlation is significant at the 0.01 level (2-tailed)