Intestinal microbiota has important effect on severity of hand foot and mouth disease in children

BMC Infectious Diseases

Table 1 Difference of virus between mild and severe cases (besides enterovirus)

Species	Mild sample (114)	Severe sample (74)	All (188)	Fisher test	Wilcoxon	Type
Groundnut ringspot and Tomato chlorotic spot virus reassortant	2	12	14	0.0003	0.0002	M < S
Cucumber green mottle mosaic virus	13	22	35	0.0021	0.0023	M < S
Porcine endogenous retrovirus E	9	18	27	0.0025	0.0009	M < S
Magnaporthe oryzae chrysovirus 1	1	8	9	0.0027	0.0019	M < S
Watermelon mosaic virus	0	6	6	0.0033	0.0021	M < S
Penicillium chrysogenum virus	8	17	25	0.0035	0.0016	M < S
Cynomolgus macaque cytomegalovirus strain Ottawa	6	14	20	0.0063	0.0032	M < S
Ictalurid herpesvirus 1	6	14	20	0.0063	0.0021	M < S
Geobacillus virus E2	0	5	5	0.0087	0.0051	M < S
Tomato spotted wilt virus	2	8	10	0.015	0.0068	M < S
Canarypox virus	0	4	4	0.0228	0.0125	M < S
Human herpesvirus 5	14	2	16	0.0298	0.0188	M > S
Oryctes rhinoceros nudivirus	2	7	9	0.0299	0.014	M < S

Mild sample (114): positive samples number in mild cases, total 114. Severe sample (74): positive sample number in severe cases, total 74. All (188): all positive sample number, total 188. Fisher test: Fisher’s exact test, p-value. Wilcoxon: wilcoxon rank-sum test, p-value. Type: the amount enriched in Mild (M > S) or Severe (M < S)

ISSN: 1471-2334