Table 3 The laboratory, radiological findings, and pathogenies of 144 hospitalized children with pertussis
From: Mortality risk factors among hospitalized children with severe pertussis
Characteristics | Total | Survivors | Deaths | P-value |
|---|---|---|---|---|
N = 144 | N = 131 | N = 13 | ||
Number | Number | Number | ||
Laboratory index | ||||
PO2 < 60 mmHg | 32 | 27 | 5 | 0.260 |
PCO2 > 50 mmHg | 35 | 28 | 7 | 0.024 |
Abnormal WBC | < 0.001 | |||
WBC < 30.0 × 109/L | 93 | 92 | 1 | |
WBC 30.0–50.0 × 109/L | 32 | 31 | 1 | |
WBC 50.0–70.0 × 109/L | 12 | 7 | 5 | |
WBC > 70.0 × 109/L | 7 | 1 | 6 | |
Absolute lymphocyte count > 20 × 109/L | 44 | 34 | 10 | < 0.001 |
Hemoglobin < 80 g/L | 14 | 10 | 4 | 0.024 |
C-reactive protein > 30 mg/L | 34 | 26 | 8 | 0.002 |
Serum albumin < 35 g/L | 27 | 21 | 6 | 0.023 |
Lactate dehydrogenase > 500 U/L | 14 | 8 | 6 | < 0.001 |
APTT > 50 s | 9 | 4 | 5 | < 0.001 |
Aspartate aminotransferase > 100 U/L | 7 | 4 | 3 | 0.017 |
Creatine kinase-MB fraction > 100 U/L | 4 | 3 | 1 | 0.318 |
Creatinine > 62 mg/d | 3 | 0 | 3 | 0.001 |
Alanine aminotransferase > 100 U/L | 2 | 1 | 1 | 0.173 |
Radiological finding | ||||
X-ray | ||||
Trachitis | 49 | 49 | 0 | 0.005 |
Pneumonia | 101 | 88 | 13 | 0.010 |
Pleural effusion | 15 | 10 | 5 | 0.003 |
Pneumothorax | 2 | 2 | 0 | 1.000 |
Echocardiography (ECHO) | < 0.001 | |||
Low pulmonary hypertension | 2 | 0 | 2 | |
Intermediate pulmonary hypertension | 5 | 0 | 5 | |
High pulmonary hypertension | 6 | 1 | 5 | |
Co-infections | ||||
Pertussis -Virus | 43 | 42 | 1 | 0.109 |
Respiratory syncytial virus | 23 | 23 | 0 | 0.129 |
Rhinovirus | 10 | 10 | 0 | 0.600 |
FA | 6 | 5 | 1 | 0.439 |
Parainfluenza | 4 | 4 | 0 | 1.000 |
Adenovirus | 0 | 0 | 0 | 1.000 |
Pertussis -Bacteria | 38 | 31 | 7 | 0.043 |
Klebsiella pneumoniae | 10 | 7 | 3 | 0.058 |
Staphylococcus aureus | 10 | 9 | 1 | 1.000 |
Haemophilus influenzae | 7 | 5 | 2 | 0.122 |
Streptococcus pneumoniae | 4 | 3 | 1 | 0.318 |
Pseudomonas aeruginosa | 3 | 3 | 0 | 1.000 |
Escherichia coli | 2 | 2 | 0 | 1.000 |
Acinetobacter baumannii | 1 | 1 | 0 | 1.000 |
Moraxella catarrhalis | 1 | 1 | 0 | 1.000 |
Pertussis—Mycoplasma pneumoniae | 14 | 11 | 3 | 0.117 |
Pertussis—Chlamydia pneumoniae | 5 | 4 | 1 | 0.381 |