From: COVID-19 hospitalizations in five California hospitals: a retrospective cohort study
Characteristic | No. patients n = 4730 | ICU admission | In-hospital mortality | ||
---|---|---|---|---|---|
Cases (%) n = 1194 (25.2) | Crude OR (95% CI) | Cases (%) n = 329 (7.0) | Crude OR (95% CI) | ||
Age in years, n (%) | |||||
18–34 | 587 (12.4) | 124 (21.1) | Reference | 10 (1.7) | Reference |
35–54 | 1204 (25.5) | 287 (23.8) | 1.17 (0.92–1.49) | 43 (3.6) | 2.14 (1.11–4.53) |
55–74 | 1861 (39.3) | 514 (23.8) | 1.43 (1.14–1.79) | 125 (6.7) | 4.15 (2.28–8.50) |
75–84 | 581 (12.3) | 160 (27.6) | 1.42 (1.09–1.86) | 76 (13.1) | 8.68 (4.66–18.04) |
85+ | 497 (10.5) | 109 (21.9) | 1.05 (0.78–1.40) | 75 (15.1) | 10.25 (5.49–21.34) |
Sex, n (%)g | |||||
Female | 2061 (43.6) | 452 (21.9) | Reference | 120 (5.8) | Reference |
Male | 2668 (56.4) | 742 (27.8) | 1.37 (1.20–1.57) | 209 (7.8) | 1.38 (1.09–1.74) |
Race/ethnicity, n (%) | |||||
White | 1218 (25.6) | 284 (23.3) | Reference | 77 (6.3) | Reference |
Black/African American | 339 (7.2) | 83 (24.5) | 1.06 (0.80–1.40) | 30 (8.9) | 1.44 (0.91–2.21) |
Hispanic/Latino | 2161 (45.7) | 551 (25.5) | 1.13 (0.96–1.33) | 144 (6.7) | 1.06 (0.80–1.41) |
Asian | 489 (10.3) | 123 (25.2) | 1.11 (0.86–1.41) | 46 (9.4) | 1.54 (1.05–2.24) |
Other/Unknown | 523 (11.1) | 153 (29.3) | 1.36 (1.08–1.71) | 32 (6.1) | 0.97 (0.62–1.46) |
Comorbidities, n (%) | |||||
No comorbidity | 1806 (38.2) | 335 (18.6) | 0.55 (0.47–0.63) | 82 (4.5) | 0.52 (0.40–0.66) |
Cancer | 191 (4.0) | 45 (23.6) | 0.91 (0.64–1.27) | 20 (10.5) | 1.60 (0.97–2.52) |
Cardiac disease | 1573 (33.3) | 582 (37.0) | 2.44 (2.13–2.80) | 188 (12.0) | 2.90 (2.32–3.65) |
Cerebrovascular disease | 367 (7.8) | 160 (43.6) | 2.49 (2.00–3.09) | 63 (17.2) | 3.19 (2.35–4.28) |
Coagulopathy | 560 (11.8) | 246 (42.9) | 2.66 (2.22–3.19) | 91 (16.3) | 3.21 (2.46–4.14) |
Deficiency anemia | 264 (5.6) | 80 (30.3) | 1.31 (0.99–1.71) | 24 (9.1) | 1.37 (0.86–2.07) |
Depression | 444 (9.4) | 116 (26.1) | 1.05 (0.84–1.31) | 31 (7.0) | 1.01 (0.67–1.45) |
Diabetes | 1137 (24.0) | 399 (35.1) | 1.90 (1.65–2.20) | 120 (10.6) | 1.91 (1.51–2.41) |
Drug use disorder | 242 (5.1) | 65 (26.9) | 1.09 (0.81–1.46) | 12 (5.0) | 0.69 (0.36–1.19) |
HIV/Aids | 444 (9.4) | 6 (15.4) | 0.54 (0.20–1.19) | 3 (7.7) | 1.12 (0.27–3.11) |
Hypertension | 1664 (35.2) | 527 (31.7) | 1.67 (1.46–1.91) | 178 (10.7) | 2.31 (1.85–2.90) |
Hypothyroidism | 340 (7.2) | 100 (29.4) | 1.26 (0.98–1.60) | 35 (10.3) | 1.60 (1.09–2.82) |
Liver disease | 416 (8.8) | 149 (35.8) | 1.75 (1.41–2.16) | 50 (12.0) | 1.98 (1.42–2.70) |
Neurological conditions | 709 (15.0) | 314 (44.3) | 2.84 (2.40–3.35) | 130 (18.3) | 4.31 (3.40–5.46) |
Obesity | 816 (17.3) | 275 (33.7) | 1.66 (1.41–1.95) | 56 (6.9) | 0.98 (0.72–1.31) |
Paralysis | 100 (2.1) | 50 (50.0) | 3.05 (2.05–4.54) | 16 (16.0) | 2.63 (1.47–4.42) |
Pregnancy | 171 (3.6) | 21 (12.3) | 0.40 (0.25–0.63) | 3 (1.8) | 0.23 (0.06–0.62) |
Psychoses | 108 (2.3) | 20 (18.5) | 0.67 (0.40–1.07) | 3 (2.8) | 0.38 (0.09–1.01) |
Pulmonary disease | 844 (17.8) | 330 (39.1) | 2.25 (1.92–2.63) | 122 (14.5) | 3.00 (2.36–3.80) |
Renal failure | 723 (15.3) | 255 (35.3) | 1.78 (1.50–2.11) | 96 (13.3) | 2.48 (1.92–3.18) |
Collagen vascular disease* | 150 (3.2) | 45 (30.0) | 1.28 (0.89–1.81) | 12 (8.0) | 1.17 (0.61–2.05) |
Smoker | 480 (10.2) | 147 (30.6) | 1.35 (1.10–1.66) | 53 (11.0) | 1.79 (1.30–2.42) |
Solid organ transplantation | 221 (4.7) | 72 (32.6) | 1.46 (1.09–1.94) | 15 (6.8) | 0.97 (0.55–1.61) |