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Table 6 Comparison between cardiac function on day of admission (day 1), day of defervescence (day 2: critical period) and on day of 2 week follow-up (day 3)

From: Cardiac evaluation in adults with dengue virus infection by serial echocardiography

Cardiac function

Dengue fever

Dengue haemorrhagic fever

Day 1

Day 2

Day 3

p-value D1 VS D2

p-value D2 VS D3

Day 1

Day 2

Day 3

p-value D1 VS D2

p-value D2 VS D3

Heart rate, mean ± SD

81.14 ± 15.28

70.09 ± 10.25

73.42 ± 11.71

 < 0.001*

0.072

79.32 ± 11.27

70.43 ± 13.85

74.65 ± 10.01

 < 0.001*

0.066

MV flow E-wave velocity, mean ± SD

0.88 ± 0.2

0.86 ± 0.17

0.91 ± 0.17

0.066

0.064

0.83 ± 0.21

0.83 ± 0.2

0.94 ± 0.17

0.797

0.001*

MV flow deceleration time, mean ± SD

179.27 ± 35.81

184.2 ± 36.85

175.71 ± 36.33

0.880

0.514

169.43 ± 45.64

194.06 ± 48.06

175.73 ± 38.84

0.023*

0.392

MV flow A-wave velocity, mean ± SD

0.64 ± 0.18

0.58 ± 0.22

0.63 ± 0.18

0.002*

0.022*

0.61 ± 0.17

1.59 ± 6.56

0.71 ± 0.2

0.342

0.379

MV annulus E-wave velocity, mean ± SD

1.5 ± 0.54

2.25 ± 3.4

1.79 ± 1.21

0.246

0.500

1.48 ± 0.54

1.63 ± 0.58

1.42 ± 0.46

0.065

0.053

E/A ratio, mean ± SD

1.51 ± 0.54

1.68 ± 0.63

1.59 ± 0.51

0.038

0.428

1.47 ± 0.54

1.63 ± 0.58

1.42 ± 0.46

0.051

0.053

e´, mean ± SD

0.12 ± 0.04

0.13 ± 0.07

0.13 ± 0.08

0.385

0.890

0.11 ± 0.03

0.1 ± 0.03

0.12 ± 0.03

0.587

0.051*

E/e´, mean ± SD

8.01 ± 2.09

8.09 ± 2.49

8.42 ± 2.42

0.797

0.295

8.34 ± 2.56

8.38 ± 2.02

8.35 ± 2.35

0.840

0.938

a´, mean ± SD

0.09 ± 0.02

0.07 ± 0.02

0.09 ± 0.02

0.009*

0.001*

0.08 ± 0.03

0.08 ± 0.03

0.08 ± 0.03

0.345

0.202

LVEF, mean ± SD

68.9 ± 5.77

69.4 ± 9.28

72.12 ± 7.63

0.822

0.022*

69.17 ± 8.58

68.68 ± 7.08

71.35 ± 6.82

0.835

0.086

LVOT mean velocity,mean ± SD

0.59 ± 0.13

0.55 ± 0.13

0.57 ± 0.12

0.081

0.063

0.57 ± 0.12

0.52 ± 0.13

0.58 ± 0.13

0.087

0.024*

Atrioventricular mean velocity, mean ± SD

0.88 ± 0.18

0.78 ± 0.14

0.83 ± 0.18

0.005*

0.018*

0.83 ± 0.14

0.82 ± 0.28

0.83 ± 0.18

0.187

0.619

Left atrial diameter, mean ± SD

3.44 ± 0.48

3.43 ± 0.43

3.47 ± 0.4

0.664

0.402

3.34 ± 0.54

3.53 ± 0.47

3.56 ± 0.48

0.026*

0.894

Cardiac index, mean ± SD

3.54 ± 1.18

2.98 ± 0.89

3.27 ± 0.95

0.003*

0.039*

3.26 ± 0.83

2.9 ± 0.84

3.29 ± 1.03

0.064

0.030*

Stroke volume, mean ± SD

69.47 ± 16.88

69.22 ± 18.14

71.56 ± 22.01

0.596

0.093

67.9 ± 16.22

69.79 ± 20.97

74.11 ± 19.03

0.429

0.233

IVC collapse, mean ± SD

69.11 ± 16.51

66.11 ± 15.34

69.33 ± 14.24

0.703

0.420

68.66 ± 14.38

64.16 ± 17.07

68.92 ± 14.70

0.213

0.230

IVCd maximum, mean ± SD

1.49 ± 0.49

1.45 ± 0.52

1.71 ± 0.57

0.740

0.005

1.58 ± 0.71

1.57 ± 0.60

1.61 ± 0.46

0.636

0.663

IVCd minimum, mean ± SD

0.44 ± 0.27

0.51 ± 0.36

0.53 ± 0.31

0.665

0.515

0.50 ± 0.34

0.55 ± 0.31

0.51 ± 0.30

0.713

0.709

  1. E/A the E(early) to A(late) ratio ventricular velocities; a´ late (atrial) diastolic mitral annular velocity, e´ early diastolic mitral annular velocity, E/e´ ratio of peak early mitral inflow velocity to early diastolic mitral annular velocity, LVEF left ventricular ejection fraction; LVOT left ventricular outflow tract, MV mitral valve, IVC inferior vena cava, IVCd inferior vena cava diameter
  2. Values are presented as means ± standard deviations. p-values correspond to paired t tests
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BMC Infectious Diseases

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