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Table 1 Clinical characteristics of mothers with chronic HBV infection

From: Characterization of T cell immunity in chronic hepatitis B virus-infected mothers with postpartum alanine transaminase flare

 

AF mothers (n = 6)

NAF mothers (n = 14)

P value

Age (years)

30.00 (25.25, 33.75)

27.00 (26.00, 29.00)

0.25

Gravidity

1.00 (1.00, 1.50)

1.00 (1.00, 2.00)

 > 0.99

Parity

1.00 (1.00, 1.50)

1.00 (1.00, 1.25)

 > 0.99

Delivery gestations (weeks)

39.00 (38.75, 39.25)

40.00 (38.00, 40.00)

0.5

Duration of AVT (days)

101.00 (91.00, 105.30)

95.00 (79.25, 105.80)

0.44

Type of delivery—no. (%)

   

 Vaginal

5 (83.33%)

11 (78.57%)

 > 0.99

 Caesarean section

1 (16.67%)

3 (21.43%)

 

Before AVT (gestational 26–28 weeks)

   

 ALT(U/L)

22.00 (15.50, 23.50)

21.00 (15.75, 24.25)

0.7

 AST(U/L)

21.00 (16.50, 29.00)

19.00 (16.75, 21.25)

0.54

Gestational 30–32 weeks

   

 ALT(U/L)

27.50 (16.00, 47.00)

16.00 (12.75, 25.25)

0.15

 AST(U/L)

29.00 (22.75, 34.00)

20.59 (16.00, 22.00)

0.05

Delivery

   

 ALT(U/L)

17.50 (11.00, 24.50)

18.00 (13.00, 20.00)

0.94

 AST(U/L)

22.00 (15.25, 25.25)

21.00 (16.25, 25.75)

0.98

Postpartum 6–8 weeks

   

 ALT(U/L)

38.00 (30.25, 98.50)

38.00 (18.75, 47.75)

0.41

 ALT(n, > 2 × ULN)

2 (33.33%)

0

0.08

 AST(U/L)

29.50 (19.00, 86.50)

25.50 (19.00, 36.00)

0.51

 AST(n, > 2 × ULN)

2 (33.33%)

0

0.08

Postpartum 15–18 weeks

   

 ALT(U/L)

106.60 (40.00, 215.80)

28.00 (23.50, 46.00)

0.03

 ALT(n, > 2 × ULN)

4 (66.67%)

0

0

 AST(U/L)

57.00 (33.75, 158.50)

24.00 (21.00, 30.00)

0

 AST(n, > 2 × ULN)

2 (33.33%)

0

0.08

  1. Data are shown as median (IQR interquartile range)
  2. AVT antepartum antiviral therapy; ALT alanine transaminase; AST aspartate aminotransferase