|
1
|
Laha [6]
|
17
|
F
|
1946
|
India
|
Fever for 2 days
|
N/A
|
N/A
|
Yes, R
|
The response to treatment
|
N/A
|
Pericardiocentesis
|
Emetine 3 g
|
Cure
|
N/A
|
|
2
|
Berberian [7]
|
59
|
M
|
1949
|
The United States
|
Malaise, weakness, diarrhea
|
N/A
|
N/A
|
No
|
Biopsy of the wall of the umbilical sinus was positive for E. hystolytica
|
N/A
|
N/A
|
Aureomycin
|
Died
|
N/A
|
|
3
|
Beemer [8]
|
27
|
M
|
1956
|
Canada
|
Left sided chest pain
|
N/A
|
N/A
|
Yes, L
|
Autopsy
|
N/A
|
N/A
|
Streptomycin, isoniazid
|
Died
|
N/A
|
|
4
|
Downie [9]
|
2
|
M
|
1960
|
Nigeria
|
Cough, discharging ears, vomiting and diarrhea
|
None
|
None
|
Yes, L
|
Amoeba was seen in the connective tissue outside the pericardium.
|
The pericardial surface of the heart was covered by thick fibrin
|
N/A
|
N/A
|
Died
|
N/A
|
|
5
|
Paulley [5]
|
51
|
M
|
1965
|
United Kingdom
|
Burning precordial pain
|
Ischemic infarction
|
Residence in India 20 years before admission
|
Yes, L
|
The response to treatment
|
N/A
|
None
|
Penicillin, chloramphenicol, chloroquine, emetine
|
Cure
|
N/A
|
|
6
|
Mullan [10]
|
73
|
M
|
1965
|
United Kingdom
|
Upper abdominal pain, anorexia, hemoptysis over 1 month
|
N/A
|
Residence in Mesopotamia 50 years before admission
|
Yes, R
|
The presence of confirmed amebic liver abscess and the response to treatment
|
None (Liver: Actively motile amoebae,containing red cells, were present)
|
Pericardiocentesis
|
Emetine
|
Died
|
None
|
|
7
|
Gelfand [11]
|
12
|
M
|
1966
|
Zimbabwe
|
Right chest pain for 3 weeks, shortness of breath, weight loss, and fever
|
None
|
None
|
Yes,
|
Bloodstained fluid, and the response to treatment
|
Dense fibrous tissue with a sparse chronic inflammatory cellular infiltrate and with a small part of its surface covered by a narrow zone of granulation tissue
|
Pericardiocentesis
|
Emetine
|
Cure
|
N/A
|
|
8
|
Kulpati [12]
|
23
|
M
|
1966
|
India
|
Prexia, upper abdominal pain, constipation
|
N/A
|
N/A
|
Yes
|
Liver aspiration contained trophozoites of E. histolytica
|
N/A
|
N/A
|
Yes, but not mentioned in detail
|
Cure
|
No recurrence 4 month after discharge
|
|
9
|
D’cruz [13]
|
21
|
M
|
1967
|
India
|
Severe retrosternal pain, vomited and fainted
|
N/A
|
N/A
|
Yes
|
Pericardial fluid contained trophozoites of E. histolytica
|
N/A
|
None
|
No
|
Died
|
N/A
|
|
10
|
Rab [14]
|
49
|
M
|
1967
|
Pakistan
|
Retrosternal pain, dyspnea
|
N/A
|
N/A
|
Yes, L
|
Anchovy sauce pus and the response to treatment
|
Fibrinous deposit
|
Pericardiocentesis
|
N/A
|
Died
|
None
|
|
11
|
Cook [15]
|
25
|
M
|
1970
|
Malaysia
|
Fever, cough, bloody sputum
|
None
|
N/A
|
Yes, R
|
The response toemetine and a strongly positive amebic fluorescent antibody test
|
None
|
Pericardiocentesis, laparotomy of left subphrenic abscess
|
Emetine and chloroquine
|
Cure
|
N/A
|
|
12
|
Ganeshananthan [16]
|
36
|
M
|
1971
|
Sri Lanka
|
Dry cough and chest pain for 3 weeks
|
N/A
|
N/A
|
N/A
|
Thick brown pus, having the consistency of typical amoebic liver abscess pus
|
N/A
|
Pericardiocentesis
|
Emetine, metronidazole, chloroquine
|
Cure
|
No recurrence 3 years after discharge
|
|
13
|
Bansal [17]
|
19
|
M
|
1971
|
India
|
Fever, dry cough, right shoulder pain for 5 days
|
N/A
|
N/A
|
Yes, R
|
Anchovy sauce pus and the response to treatment
|
None
|
Pericardiocentesis
|
Emetine, chloroquine, di-iodohydroxy quinoline
|
Cure
|
No recurrence 16 months after discharge
|
|
14
|
Kapoor [18]
|
27
|
M
|
1972
|
India
|
High fever with pain in the left chest and subcostal region
|
Gastro-pericardial
fistula
|
N/A
|
Yes, L
|
N/A (Stool: trophozoites of E. histolytica)
|
N/A
|
Pericardiocentesis
|
Intramuscular emetine
|
Cure
|
NA
|
|
15
|
Kapoor [18]
|
30
|
M
|
1972
|
India
|
General weakness, pain in the abdomen and swelling in the epigastrium for 3 weeks
|
N/A
|
N/A
|
Yes, L
|
N/A (Stool: trophozoites of E. histolytica)
|
N/A
|
Pericardiocentesis
|
Emetine, chloroquine
|
Cure
|
N/A
|
|
16
|
Kapoor [18]
|
34
|
M
|
1972
|
India
|
Pain in the epigastrium and right lumber region for 2 months
|
N/A
|
N/A
|
Yes
|
Anchovy sauce pus from the front of pericardial cavity
|
N/A
|
Pericardiocentesis, thoracotomy
|
Emetine
|
Cured
|
N/A
|
|
17
|
Kapoor [18]
|
35
|
M
|
1972
|
India
|
Sudden onset of severe generalized chest pain and dyspnea for 12 h
|
N/A
|
N/A
|
Yes, L
|
N/A (Liver: trophozoites of E. hystolytica)
|
Yes
|
Pericardiocentesis
|
N/A
|
Died
|
N/A
|
|
18
|
Kapoor [18]
|
25
|
M
|
1972
|
India
|
Pyrexia for 5 days
|
N/A
|
N/A
|
N/A
|
N/A
|
N/A
|
Pericardiocentesis
|
Dehydroemetine, chloroquine
|
Cured
|
No recurrence 3 weeks after discharge
|
|
19
|
Kapoor [18]
|
50
|
M
|
1972
|
India
|
Fever for 2 months and pain in the right hypochonrium
|
N/A
|
N/A
|
Yes, L
|
Anchovy sauce pus from the pericardial cavity
|
N/A
|
Pericardiocentesis
|
Emetine, chloroquine
|
Cured
|
No recurrence two years after discharge
|
|
20
|
Spiegel [19]
|
48
|
M
|
1972
|
The United States
|
Abdominal pain of right upper quadrant
|
N/A
|
N/A
|
Yes, R
|
Pericardial fluid contained trophozoites of E. histolytica
|
N/A
|
N/A
|
Metronidazole and chloroquine
|
Cure
|
N/A
|
|
21
|
Heller [20]
|
42
|
F
|
1972
|
United States
|
Dyspnea, weight loss, left upper abdominal pain for 8 days
|
N/A
|
Move from Mississippi to Chicago when she was 3 years old
|
Yes, L
|
Anchovy sauce pus, the response to treatment, and indirect hemagglutination test (1:2560)
|
Fibrinous pericarditis
|
Pericardiocentesis followed by pericardiectomy
|
Metronidazole 750 mg thrice daily for 3 weeks
|
Cure
|
N/A
|
|
22
|
Heller [20]
|
47
|
M
|
1972
|
United States
|
Retrosternal pain, sweating, dyspnea for 1 day
|
N/A
|
Move from Mexico to Chicago 5 months previously
|
Yes, L
|
Anchovy sauce pus, the response to treatment, and indirect hemagglutination test (1:5128)
|
Fibrinous pericarditis
|
Pericardiectomy
|
Emetine (next day changed to dehydroemetine), chloroquine
|
Died
|
None
|
|
23
|
Anderson [21]
|
N/A
|
M
|
1972
|
United States
|
Left pleuritic chest pain, jaundice for 10 days
|
None
|
N/A
|
Yes, L
|
Anchovy sauce pus and the response to treatment
|
None
|
Pericardiocentesis followed by pericardiectomy
|
N/A
|
Cure
|
N/A
|
|
24
|
Suryanarayan [22]
|
40
|
M
|
1973
|
India
|
Pain in the epigasric region and hypochondrium for one mouth, and dysponea for 1 week
|
N/A
|
N/A
|
Yes, L
|
N/A
|
N/A
|
Pericardiocentesis
|
Dehydroemetine, tetracyclines, chloroquine and didoquin
|
Cure
|
N/A
|
|
25
|
Suryanarayan [22]
|
45
|
M
|
1973
|
India
|
Fever for 3 months and dyspnea for 2 days
|
N/A
|
N/A
|
Yes, L
|
Pericardial fluid contained trophozoites of E. histolytica
|
N/A
|
None
|
N/A
|
Died
|
N/A
|
|
26
|
Lewis [23]
|
35
|
M
|
1973
|
N/A
|
N/A
|
N/A
|
N/A
|
N/A
|
N/A
|
N/A
|
N/A
|
N/A
|
N/A
|
N/A
|
|
27
|
Ganeshananthan [16]
|
33
|
M
|
1974
|
Sri Lanka
|
Left-sided chest pain and shortness of breath for 2 weeks
|
N/A
|
N/A
|
N/A
|
The fluorescent antibody test was positive
|
N/A
|
Pericardiocentesis
|
Emetine, metronidazole
|
Cure
|
No recurrence 6 months after discharge
|
|
28
|
Ganeshananthan [16]
|
43
|
M
|
1974
|
Sri Lanka
|
Shortness of breath and pain in the chest and abdomen for 18 days
|
N/A
|
N/A
|
Yes
|
Typical amoebic pus was drawn out from needling of the pericardium
|
N/A
|
Pericardiocentesis
|
Emetine, tetracycline, metronidazole
|
Cure
|
N/A
|
|
29
|
Ganeshananthan [16]
|
32
|
N/A
|
1974
|
Sri Lanka
|
Pain in the left upper abdomen for 2 months
|
N/A
|
N/A
|
N/A
|
The fluorescent antibody test was
positive
|
N/A
|
Pericardiocentesis
|
Emetine and chloroquine followed by metronidazole
|
Cure
|
N/A
|
|
30
|
Guimaraes [24]
|
33
|
M
|
1974
|
Brazil
|
Fever, chills, dry cough, retrosternal pain, weight loss, dyspnea, diarrhea
|
N/A
|
N/A
|
Yes, L
|
Anchovy sauce pus and the response to treatment
|
N/A
|
Pericardiocentesis
|
Chloroquine 2 g daily for 7 days, followed by 500 mg daily for 23 days, metronidazole 2 g daily for 30 days, emetine hydroxychloroquine 60 mg daily for 10 days plus the injection of 75% hypaque into the pericardial cavity
|
Cure
|
N/A
|
|
31
|
Faerber [25]
|
35
|
M
|
1974
|
South Africa
|
Pleuritic chest pain, productive cough, hemoptysis for 2 months
|
N/A
|
N/A
|
Yes, R and L
|
N/A
|
N/A
|
N/A
|
N/A
|
Cure
|
N/A
|
|
32
|
Haranath [26]
|
55
|
M
|
1974
|
India
|
Exertional dyspnea, distention of the abdomen and edema of the left upper limb for 10 days
|
Rheumatic fever
|
N/A
|
N/A
|
Anchovy sauce pus from the cardiac cavity
|
N/A
|
Pericardiocentesis
|
Dehydroemetine, metronidazole
|
Cure
|
NA
|
|
33
|
Ganesan [3]
|
40
|
M
|
1975
|
India
|
Progressive general weakness, chest pain, dyspnea for 20 days
|
N/A
|
N/A
|
Yes, L
|
Anchovy sauce pus and the response to treatment
|
None
|
Pericardiocentesis
|
Dehydromethine 30 mg daily for 10 days, chloroquine 250 mg thrice daily for 10 days, and metronidazole 1200 mg daily for ten days
|
Cure
|
N/A
|
|
34
|
Agrawal [1]
|
40
|
M
|
1975
|
India
|
Fever, cough, pain in right hypochondrium, fatigue for 2 months
|
None
|
N/A
|
Yes, L
|
Aspiration of anchovy source pus from the cardiac cavity
|
The nonspecific chronic inflammatory reaction of the pericardium
|
Pericardiocentesis
|
Metronidazole 400 mg thrice daily
|
Died
|
None
|
|
35
|
Agrawal [1]
|
25
|
N/A
|
1975
|
India
|
Pain in the upper abdomen and dry cough for 2 weeks
|
None
|
N/A
|
Yes, L
|
Aspiration of anchovy source pus from the cardiac cavity
|
An actively inflamed fibrosing pyopericardium of nonspecific nature
|
Pericardiocentesis
|
Metronidazole 400 mg thrice daily
|
Cure
|
No recurrence 6 months after discharge
|
|
36
|
Kulpati [27]
|
34
|
M
|
1976
|
India
|
Moderately high intermittent fever and dull aching pain in right hypochondrium for 1 month
|
History of amoebic dysentery about 8 months back
|
N/A
|
Yes, L
|
The pericardial fluid was chocolate colored. The direct smear and culture of pericardial fluid demonstrated E. hystolytica
|
N/A
|
Pericardiocentesis
|
Metronidazole and
emetine
|
Died
|
N/A
|
|
37–63
|
Adams EB1-27 [28]
|
N/A
|
N/A
|
1977
|
South Africa
|
N/A
|
N/A
|
N/A
|
8 patients (mostly L)
|
N/A
|
N/A
|
N/A
|
N/A
|
Cure (n = 19) Died (n = 8)
|
N/A
|
|
64
|
Muralidar [29]
|
19
|
F
|
1977
|
India
|
Pyrexia and pain in the right upper abodomen for 2 weeks and breathlessness for 4 days
|
None
|
N/A
|
N/A
|
Anchovy sauce pus from the cardiac cavity
|
N/A
|
Pericardiocentesis
|
Emetine, metronidazole, and tetracycline
|
Died
|
N/A
|
|
65
|
Muralidar [29]
|
52
|
M
|
1977
|
India
|
Chest pain and breathlessness since 3 days
|
History of amoebic dysentery
|
N/A
|
N/A
|
Anchovy sauce pus from the cardiac cavity, serum indirect hemagglutination
|
N/A
|
Pericardiocentesis
|
Emetine and metronidazole
|
Cure
|
No recurrence 6 weeks after discharge
|
|
66
|
Kundu [30]
|
25
|
F
|
1978
|
India
|
Pain in right hypochondrium associated with moderately high intermittent fever for 15 days and difficulty in breathing for 1 week
|
None
|
N/A
|
Yes, L
|
Serum gel diffusion test, chocolate pus
|
N/A
|
Pericardiocentesis
|
Metronidazole followed by chloroquine
|
Cure
|
No recurrence 4.5 months after discharge
|
|
67
|
Bellosillo [31]
|
37
|
M
|
1978
|
Philippine
|
Shortness of breath
|
N/A
|
N/A
|
Yes
|
Pericardial fluid contained trophozoites of E. histolytica
|
N/A
|
Pericardiocentesis
|
Tinidazole
|
Cure
|
No recurrence 3 months after discharge
|
|
68–72
|
Verghese 1-5 [32]
|
N/A
|
N/A
|
1979
|
India
|
N/A
|
N/A
|
N/A
|
N/A
|
N/A
|
N/A
|
Pericardiocentesis (n = 1), pericardiotomy (n = 3)
|
N/A
|
Cure (n = 3) Died (n = 2)
|
N/A
|
|
73
|
Almeida [33]
|
35
|
M
|
1979
|
India
|
Epigastric pain for 1 month and swelling in upper abdomen for 15 days
|
None
|
N/A
|
Yes, L
|
Anchovy sauce pus and the response to treatment
|
N/A
|
Pericardiocentesis
|
Emetine and chloroquine
|
Cure
|
No recurrence 9 months after discharge
|
|
74
|
Almeida [33]
|
20
|
M
|
1979
|
India
|
Shortness of breath and left chest pain for 3 days
|
None
|
N/A
|
Yes, L
|
Anchovy sauce pus from the cardiac cavity
|
Pericardium was thickened
|
Pericardiocentesis
|
Emetine, and oxytetracycline
|
Died
|
N/A
|
|
75
|
Almeida [33]
|
25
|
M
|
1979
|
India
|
Left chest pain, cough, and fever for 1 month
|
None
|
N/A
|
Yes, L
|
Anchovy sauce pus from the cardiac cavity
|
N/A
|
Pericardiocentesis
|
N/A
|
Died
|
N/A
|
|
76
|
Almeida [33]
|
40
|
M
|
1979
|
India
|
Anorexia, fever, and right chest pain for 15 days
|
None
|
N/A
|
Yes, L
|
N/A
|
Autopsy revealed liver abscess with pericarditis and cardiac tamponade
|
None
|
N/A
|
Died
|
N/A
|
|
77
|
Almeida [33]
|
50
|
F
|
1979
|
India
|
Jaundice and fever for 1 month
|
None
|
N/A
|
Yes, L
|
Bloodstained fluid
|
N/A
|
Pericardiotomy
|
Emetine and metronidazole
|
Died
|
N/A
|
|
78–89
|
Tyagi 1–12 [34]
|
4–55
|
M:9 F:3
|
1980
|
India
|
Fever (n = 10), dyspnea (n = 5), cough (n = 4), diarrhea (n = 3
|
N/A
|
N/A
|
Yes, L: 5, R: 4
|
Anchovy sauce pus from the cardiac cavity (n = 2), pericardial fluid contained trophozoites of E. histolytica (n = 2)
|
N/A
|
Pericardiocentesis
|
N/A
|
Cure (n = 4) Died (n = 8)
|
N/A
|
|
90
|
Gupta [35]
|
43
|
M
|
1980
|
India
|
Dyspnea, chest pain
|
N/A
|
N/A
|
No
|
Pericardial fluid contained trophozoites of E. histolyticaAutopsy
|
N/A
|
Pericardiocentesis
|
N/A
|
Cure
|
N/A
|
|
91
|
Kala [36]
|
35
|
M
|
1980
|
India
|
Dyspnea, diarrhea
|
N/A
|
N/A
|
Yes
|
Pericardial fluid contained trophozoites of E. histolyticaAutopsy
|
N/A
|
Pericardiocentesis followed by pericardiectomy
|
Emetine, Streptomycin, isoniazid
|
Cure
|
N/A
|
|
92–101
|
Ibarra-Perez 1–10 [37]
|
N/A
|
N/A
|
1981
|
Mexico
|
N/A
|
N/A
|
N/A
|
N/A
|
N/A
|
N/A
|
N/A
|
N/A
|
N/A
|
N/A
|
|
102
|
Adeyemo [38]
|
N/A
|
N/A
|
1984
|
Nigeria
|
N/A
|
N/A
|
N/A
|
Yes, L
|
N/A
|
N/A
|
Pericardiocentesis
|
N/A
|
Died
|
N/A
|
|
103
|
Adeyemo [38]
|
N/A
|
N/A
|
1984
|
Nigeria
|
N/A
|
N/A
|
N/A
|
Yes, L
|
N/A
|
N/A
|
Pericardiocentesis
|
N/A
|
Died
|
N/A
|
|
104
|
Farer [39]
|
23
|
M
|
1984
|
Vietnam
|
Dyspnea, chest pain
|
N/A
|
Indonesia
|
N/A
|
Microscopic finding of amebic trophozoites, anchovy sauce pus, and the response to treatment
|
None
|
Pericardiocentesis
|
Specific chemotherapy for amebiasis
|
Cure
|
N/A
|
|
105
|
Shanker [40]
|
30
|
M
|
1985
|
India
|
Irregular fever and dull aching oain in right hypochondrium for 1 month
|
History of amoebic dysentery about 6 months back
|
N/A
|
N/A
|
Pericardial fluid contained trophozoites of E. histolyticaAutopsy
|
N/A
|
Pericardiocentesis
|
Metronidazole, ampicillin, emetine hydrochloride
|
Cure
|
N/A
|
|
106
|
Pirie [41]
|
N/A
|
N/A
|
1986
|
South Africa
|
N/A
|
N/A
|
N/A
|
N/A
|
N/A
|
N/A
|
N/A
|
N/A
|
N/A
|
N/A
|
|
107
|
Baid [42]
|
48
|
M
|
1987
|
India
|
Dyspnea, left chest pain, fever, edema of the feet, weakness for 1 month
|
N/A
|
N/A
|
Yes, R
|
Anchovy sauce pus and the response to treatment
|
Subepicardial fat-containing proliferating fibroblasts and lymphocytic infiltrate
|
Pericardiocentesis followed by pericardiectomy
|
Metronidazole
|
Cure
|
None
|
|
108
|
Strang [43]
|
N/A
|
N/A
|
1987
|
South Africa
|
N/A
|
N/A
|
N/A
|
Yes
|
N/A
|
N/A
|
N/A
|
N/A
|
N/A
|
N/A
|
|
109
|
Blackett [44]
|
50
|
M
|
1988
|
Cameroon
|
Left-sided chest pain, dyspnea, abdominal distension, edema for several days
|
N/A
|
N/A
|
None
|
The positive serological tests (1/1024) for amoebiasis, the appearance of the fluid obtained on tapping the pericardium, and the response to treatment
|
None
|
None
|
Metronidazole and chloroquine
|
Died
|
None
|
|
110
|
Vanachayangkul [45]
|
51
|
M
|
1989
|
Thailand
|
Epigastric oppression and fever for 1 week beginning with severe pain, occasionally colicky in nature without nausea or vomiting
|
N/A
|
N/A
|
Yes
|
Aspiration of pericardial effusion yielded 350 mL of brownish grey pus with numerous trophozoites of active motile E. hystolytica
|
N/A
|
Pericardiocentesis followed by pericardiotomy
|
Metronidazole and cefotiam and amikacin
|
Cure
|
N/A
|
|
111
|
Lami [46]
|
26
|
F
|
1989
|
Italy
|
Fever, headache, left chest pain
|
None
|
Tunisia for 2 months
|
None
|
Indirect hemagglutination test
|
N/A
|
N/A
|
Metronidazole 2 g daily for 10 days
|
Cure
|
N/A
|
|
112
|
Supe [47]
|
40
|
M
|
1991
|
India
|
N/A
|
N/A
|
N/A
|
Yes
|
Elisa test for E. histolytica antibody was positive
|
N/A
|
Pericardiocentesis
|
Emetine, metronidazole and amikacin
|
Cure
|
N/A
|
|
113
|
Gomersall [48]
|
28
|
M
|
1994
|
United Kingdom
|
Fever, night sweats, pyrexia, and right-sided pleuritic chest pain for 6 weeks
|
None
|
Stationed in Kenya
|
Yes, L
|
A fluorescent antibody test for E. hystolytica was positive (titer 1/320) and amoebic enzyme immunoassay was positive at 120 %
|
None
|
Pericardiocentesis
|
Metronidazole for 10 days and diloxanide for 10 days
|
Cure
|
No recurrence 6 months after discharge
|
|
114
|
Perna [49]
|
37
|
M
|
1994
|
Italy
|
Fever, malaise, weight loss
|
Drug addiction
|
N/A
|
Yes, L
|
A bacteriological specimen from the pericardial fluid yielded E. hystolytica, anchovy sauce pus, and the response to treatment
|
N/A
|
Pericardiectomy
|
Chloroquine
|
N/A
|
N/A
|
|
115
|
Shandera [50]
|
64
|
M
|
1998
|
India
|
Epigastric pain and pleuritic pain for 6 weeks
|
N/A
|
N/A
|
Yes, L
|
Positive serological tests for amoebiasis
|
None
|
Pericardiocentesis
|
Metronidazole and diiodoquinolol
|
Cure
|
N/A
|
|
116
|
Chao [4]
|
44
|
M
|
1998
|
Taiwan
|
Dyspnea for the previous 2 days, mucoid diarrhea for 3 days
|
Chronic schizophrenia
|
N/A
|
Yes, L
|
Amebic antibodies by hemagglutination test (1:16,384)
|
Fibrinous exudate with polymorphic neutrophilic cell infiltration
|
Pericardiectomy
|
Metronidazole 500 mg 4 times daily for 2 weeks
|
Cure
|
No recurrence 1-year after discharge
|
|
117
|
Wiwanitkit [51]
|
N/A
|
N/A
|
2008
|
Thailand
|
Chest pain, discomfort, and arrhythmia
|
N/A
|
N/A
|
Yes
|
N/A
|
N/A
|
N/A
|
N/A
|
Cure (n = 2) Died (n = 1)
|
N/A
|
|
118
|
Murali [52]
|
38
|
M
|
2011
|
India
|
Fever and right hypochondrial pain for 10 days
|
N/A
|
N/A
|
Yes, R
|
Positive linked immunosorbent assay for E. hystolytica (both IgM and IgG)
|
None
|
Pericardiocentesis
|
Meropenem, metronidazole
|
Cure
|
N/A
|
|
119
|
Amine [53]
|
38
|
M
|
2015
|
Morocco
|
Fever, shortness of breath, and leg swelling for 2 months
|
Recurrent diarrhea
|
N/A
|
None
|
Trophozoites of E. hystolytica (pleural effusion)
|
None
|
Pericardiectomy
|
Metronidazole 500 mg trice daily
|
N/A
|
N/A
|
|
120
|
Agarwal [54]
|
25
|
M
|
2019
|
India
|
Abdominal pain and fever for 1 month
|
None
|
N/A
|
Yes, L
|
Anchovy sauce pus, PCR for E. hystolytica from the pericardial cavity
|
N/A
|
Pericardiocentesis, pleural pericardial window
|
Metronidazole
|
Cure
|
No recurrence at 1 year after discharge
|
|
121
|
Keleş [55]
|
25
|
M
|
2020
|
India
|
Fever, chills, and pain in the upper abdomen for 1 month
|
N/A
|
N/A
|
Yes, L
|
Reddish-brown pus from the cardiac cavity, positive serological test for amebiasis, and PCR for E. hystolytica
|
N/A
|
Pericardiocentesis
|
Metronidazole followed by oral luminal amebicide diloxanide
|
Cure
|
No recurrence 1-year after discharge
|
|
122
|
Francis [56]
|
15
|
M
|
2020
|
Turkey
|
Diarrhea and abdominal pain for 2 days
|
None
|
N/A
|
None
|
E. hystolytica trophozoites and cysts in fresh stool, and the response to treatment
|
None
|
None
|
Metronidazole (30 mg/kg/day)
|
Cure
|
No recurrence 6-month after discharge
|
|
123
|
Raza [57]
|
7
|
M
|
2020
|
Pakistan
|
Fever and abdominal pain for 15 days and diarrhea for 3 days
|
Acute gastroenteritis
|
N/A
|
Yes, L
|
Cysts of E. histolytica and positive enzyme-linked immunosorbent assay in stool
|
None
|
None
|
Metronidazole for 14 days, followed by diloxanide furoate for the next 7 days
|
Cure
|
No recurrence 2-week after discharge
|
|
Current case
|
Matsuoa
|
71
|
M
|
2019
|
Japan
|
Epigastric pain, fatigue for 2 months
|
Essential thrombocytosis treated with anagrelide
|
Asia
|
None
|
Positive serological test for amebiasis, PCR for E. hystolytica from the pericardial cavity
|
N/A
|
Pericardiocentesis
|
Metronidazole 750 mg trice daily for 2 weeks, followed by paromomycin 500 mg trice daily for 10 days
|
Cure
|
No recurrence at 1 year after discharge
|
