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Table 2 Risk factors for disease progression in patients with COVID-19

From: Risk factors for disease progression in Japanese patients with COVID-19 with no or mild symptoms on admission

Factor Univariate Multivariate
OR (95% CI) P value OR (95% CI) P value
Age (per 10 years) 1.495 (1.243–1.808)  < 0.001 1.538 (1.219–1.949)  < 0.001
Sex 2.494 (1.212–5.132) 0.013   
Overweight (BMI ≥ 25) 4.108 (2.103–8.025)  < 0.001 3.260 (1.463–7.265) 0.0038
Asthma 0.984 (0.371–2.606) 0.97   
Hypertension 5.170 (2.577–10.37)  < 0.001   
Cardiovascular disease 2.919 (1.191–7.156) 0.019   
Diabetes 3.594 (1.473–8.773) 0.0050 2.851 (1.056–7.698) 0.039
NLR 1.057 (0.970–1.153) 0.21   
CRP 1.272 (1.132–1.430)  < 0.001   
LDH 1.010 (1.005–1.015)  < 0.001   
Creatinine 9.551 (2.327–39.20) 0.0017   
Ferritin 1.003 (1.002–1.004)  < 0.001 1.002 (1.001–1.004)  < 0.001
D-dimer 1.009 (0.936–1.088) 0.81   
  1. Risk factors associated with disease severity were analyzed using a logistic regression model. P < 0.05 was considered statistically significant
  2. OR odds ratio, CI confidence interval, BMI body mass index, NLR neutrophil-to-lymphocyte ratio, CRP C-reactive protein, LDH lactate dehydrogenase