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Table 8 Differences between MDR-positive and MDR-negative patients

From: Epidemiology of patients with central nervous system infections, mainly neurosurgical patients: a retrospective study from 2012 to 2019 in a teaching hospital in China

Characteristics Total (N = 72) MDR-positive (N = 49) MDR-negative (N = 23) P
Age (years) 49.7 ± 18.3 50.8 ± 19.1 47.3 ± 16.6 0.459
Sex
 Male 54 (75.0) 35 (71.4) 19 (82.6) 0.307
 Female 18 (25.0) 14 (28.6) 4 (17.4)
Days from hospitalization to detection of bacteria 9.5 (3.0–17.8) 10.0 (4.5–17.5) 5.0 (1.0–18.0) 0.258
Comorbidity
 Pulmonary infection 35 (48.6) 27 (55.1) 8 (34.8) 0.108
 Hypertension 29 (40.3) 23 (46.9) 6 (26.1) 0.093
 Hydrocephalus 26 (36.1) 20 (40.8) 6 (26.1) 0.225
 Intracranial hemorrhage 19 (26.4) 18 (36.7) 1 (4.3) 0.004
 Diabetes 10 (13.9) 8 (16.3) 2 (8.7) 0.612
Surgery
 Yes 50 (69.4) 39 (79.6) 11 (47.8) 0.006
 No 22 (30.6) 10 (20.4) 12 (52.2)
Invasive device
 External ventricular drainage/Lumbar cistern drainage 41 (56.9) 34 (69.4) 7 (30.4) 0.002
 Catheter 57 (79.2) 42 (85.7) 15 (65.2) 0.092
CSF data
 ADA level (U/L) 15.50 (4.33–30.95) 23.00 (5.95–36.35) 6.00 (1.50–17.10) 0.001
 Glucose level (mmol/L) 1.71 (0.21–2.98) 1.65 (0.17–2.66) 2.11 (0.23–3.40) 0.476
 Chlorine level (mmol/L) 116.68 ± 9.27 116.03 ± 9.5 118.04 ± 8.88 0.395
 Protein level (g/L) 2.37 (1.12–4.01) 3.06 (1.65–4.11) 1.06 (0.67–2.57) < 0.001
 Leukocyte count (× 106/L) 340.0 (52.5–2400.0) 480.0 (120.0–2400.0) 60.0 (8.0–2420.0) 0.033
 Erythrocyte count (× 106/L) 395.0 (10.0–4787.5) 800.0 (70.0–6675.0) 25.0 (0.0–1560.0) 0.052
Blood data
 White blood cell level (× 109/L) 13.13 ± 6.11 13.3 ± 5.9 12.9 ± 6.7 0.798
 Neutrophils level (× 109/L) 10.55 (6.94–13.48) 11.20 (7.84–13.14) 9.48 (6.21–13.59) 0.48
 Percentage of neutrophils 85.21 (78.86–88.05) 85.50 (80.01–87.82) 83.5 (75.9–90.3) 0.503