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Table 8 Differences between MDR-positive and MDR-negative patients

From: Epidemiology of patients with central nervous system infections, mainly neurosurgical patients: a retrospective study from 2012 to 2019 in a teaching hospital in China

Characteristics

Total (N = 72)

MDR-positive (N = 49)

MDR-negative (N = 23)

P

Age (years)

49.7 ± 18.3

50.8 ± 19.1

47.3 ± 16.6

0.459

Sex

 Male

54 (75.0)

35 (71.4)

19 (82.6)

0.307

 Female

18 (25.0)

14 (28.6)

4 (17.4)

Days from hospitalization to detection of bacteria

9.5 (3.0–17.8)

10.0 (4.5–17.5)

5.0 (1.0–18.0)

0.258

Comorbidity

 Pulmonary infection

35 (48.6)

27 (55.1)

8 (34.8)

0.108

 Hypertension

29 (40.3)

23 (46.9)

6 (26.1)

0.093

 Hydrocephalus

26 (36.1)

20 (40.8)

6 (26.1)

0.225

 Intracranial hemorrhage

19 (26.4)

18 (36.7)

1 (4.3)

0.004

 Diabetes

10 (13.9)

8 (16.3)

2 (8.7)

0.612

Surgery

 Yes

50 (69.4)

39 (79.6)

11 (47.8)

0.006

 No

22 (30.6)

10 (20.4)

12 (52.2)

Invasive device

 External ventricular drainage/Lumbar cistern drainage

41 (56.9)

34 (69.4)

7 (30.4)

0.002

 Catheter

57 (79.2)

42 (85.7)

15 (65.2)

0.092

CSF data

 ADA level (U/L)

15.50 (4.33–30.95)

23.00 (5.95–36.35)

6.00 (1.50–17.10)

0.001

 Glucose level (mmol/L)

1.71 (0.21–2.98)

1.65 (0.17–2.66)

2.11 (0.23–3.40)

0.476

 Chlorine level (mmol/L)

116.68 ± 9.27

116.03 ± 9.5

118.04 ± 8.88

0.395

 Protein level (g/L)

2.37 (1.12–4.01)

3.06 (1.65–4.11)

1.06 (0.67–2.57)

< 0.001

 Leukocyte count (× 106/L)

340.0 (52.5–2400.0)

480.0 (120.0–2400.0)

60.0 (8.0–2420.0)

0.033

 Erythrocyte count (× 106/L)

395.0 (10.0–4787.5)

800.0 (70.0–6675.0)

25.0 (0.0–1560.0)

0.052

Blood data

 White blood cell level (× 109/L)

13.13 ± 6.11

13.3 ± 5.9

12.9 ± 6.7

0.798

 Neutrophils level (× 109/L)

10.55 (6.94–13.48)

11.20 (7.84–13.14)

9.48 (6.21–13.59)

0.48

 Percentage of neutrophils

85.21 (78.86–88.05)

85.50 (80.01–87.82)

83.5 (75.9–90.3)

0.503