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Table 1 Indicators of the feasibility of patient recruitment and data collection procedures

From: Evaluation of a standardised protocol to measure the disease burden of respiratory syncytial virus infection in young children in primary care

 

Italy

Netherlands

Feasibility patient recruitment

 Number of children swabbed (n)

293

152

 Number of RSV positive children (n,%)

119 (41%)

32 (21%)

 Response rate Day-14 (n, %)

116 (98%)

12 (38%)

 Response rate Day-30 (n, %)

116 (98%)

11 (34%)

Feasibility data collection procedures

N = 119

N = 12

 Days between disease onset and swab (median, IQR)

2 (1–3.5)

3 (2–4.5)

 Days between swab and Day-14 (median, IQR)

17 (14.5–20.5)

20 (16.5–30.5)

 Days between swab and Day-30 (median, IQR)

32.5 (30.5–35)

36.5 (29.5–39)

 Having symptoms at Day-14 (n, %)

40 (34%)

8 (67%)

 Questionnaire duration, Day-14 (minutes)

7 (5–10)

4 (3–5)

 Questionnaire duration, Day-30 (minutes)

10 (7–15)

4 (3–8)

  1. Note. In Italy all parents gave informed consent before swabbing, while in the Netherlands parents were asked for informed consent after the child was tested RSV positive (Fig. 1). In the Netherlands, 19 parents of RSV positive children did not respond on the study letter asking for informed consent, and 1 parent provided informed consent but did not complete the Day-14 questionnaire. This is reflected in the response rate at Day-14