Fig. 2
Final protocol to measure the clinical and socio-economic disease burden in primary care in young children. Children can be selected via a network of pediatricians or GPs involved in study (dark blue boxes), or via a routine influenza surveillance network in primary care (light blue boxes). Parents of RSV positive children will complete the Day-14 and Day-30 questionnaires (grey boxes). In children selected via the routine influenza surveillance program informed consent for swab collection is obtained via the routine surveillance procedures. Parents of RSV positive children are asked for informed consent for this study and will be asked to complete the Day-14 and Day-30 questionnaires. a Questions related to medical history are added to the Day-14 questionnaire in countries where it is not possible to complete the questions in the Day-1 questionnaire for practical reasons. b Quality of life is measured with one question on the child’s health status of today and one question on the guardian’s health status of today measured on a Visual Analogue Scale. c Topics 1 (health care use) and 3 (socio-economic impact) in the Day-30 questionnaire are introduced with a general question to examine whether the more detailed questions are required