Genomic surveillance of antimicrobial resistant bacterial colonisation and infection in intensive care patients

BMC Infectious Diseases

Table 1 Colonisation and infection episodes by species

Species	Total colonisation episodes (n baseline)	Infection episodes
Species	Total colonisation episodes (n baseline)	Total	Pt colonised with same strain (n baseline)	Pt colonised at baseline (%)	Pt not colonised at baseline (%)
VRE
Enterococcus faecium	33 (25)	2	0	0	1 (0.4%)
3GC-resistant GN
Escherichia coli	36 (33)	10	1 (0)	2 (6%)	4 (2%)
Klebsiella pneumoniae	4 (2)	7	3 (2)	2 (100%)	3 (1%)*
Pseudomonas aeruginosa	3 (2)	2	1 (1)	2 (100%)	0 (0%)*
Enterobacter hormaechei	4 (3)	3	0	0	1
Klebsiella aerogenes	4 (1)	3	0	0	1
Enterobacter asburiae	0	2	0	0	1
Stenotrophomonas maltophilia	0	2	0	0	1
Serratia marcescens	1 (0)	2	0	0	0
Achromobacter xylosoxidans	0	1	0	0	1
Burkholderia cenocepacia	0	1	0	0	1
Citrobacter freundii	2 (2)	1	0	0	0
Citrobacter portucalensis	1 (1)	0	0	0	0
Enterobacter kobei	1 (0)	0	0	0	0
Escherichia marmotae	1 (1)	0	0	0	0
Klebsiella oxytoca	4 (4)	0	0	0	0
Morganella morganii	1 (0)	0	0	0	0

* p < 0.00005 for association between colonisation at baseline and infection with same species (proportion test). Distinct episodes of colonisation and infection were defined as those with a unique combination of patient ID, specimen type, species and multi-locus sequence type. Colonisation episodes are expressed as total detected and number detected at baseline (within first 2 days after ICU admission). Strains were defined on the basis of chromosomal SNVs (≤7 SNVs between isolates). Pt patient, VRE vancomycin-resistant enterococci

ISSN: 1471-2334