Fig. 3

3GCR-GN and VRE strain diversity. (A) Bar plot showing the number of unique multi-locus sequence types (STs) identified for each third-generation cephalosporin-resistant Gram-negative (3GCR-GN) species plus vancomycin-resistant E. faecium (VRE) Bars are coloured as indicated in the legend. (B, C) Pairwise single nucleotide variants (SNVs) for pairs of isolates assigned to the same ST for 3GCR-GN species (B) and VRE (C). Grey points indicate pairs of isolates from the same patient (pt), pink and blue points indicate pairs of isolates from different patients for 3GCR-GN and VRE isolates, respectively. Grey dashed lines indicate the SNV thresholds used to define putative transmissions (n ≤ 20 SNVs for 3GCR-GN and n ≤ 3 SNVs for VRE, see Results for details). *E. hormaechei multi-locus sequence typing was performed using the Enterobacter cloacae scheme, which covers both species