1230778
|
mazF3
|
0.9703
|
ACC
|
65
|
ATC
|
T/I
|
unknown
|
Toxic component of a type II toxin-antitoxin (TA) system.
|
| | | | | | | |
It dramatically increases persister cell formation
|
| | | | | | | |
in M.smegmatis upon challenge with gentamicin or kanamycin.
|
| | | | | | | |
Probable propionyl-CoA carboxylase beta chain 4 AccD4.
|
4254431
|
accD4
|
0.9644
|
GAC
|
506
|
GAT
|
D/D
|
Cell wall
|
mycolate cell wall layer assembly.
|
3408150
|
Rv3047c
|
0.9644
|
ACA
|
53
|
GCA
|
T/A
|
unknown
|
Hypothetical unknown protein.
|
3027798
|
Rv2714
|
0.9644
|
GTG
|
245
|
GCG
|
V/A
|
plasma membrane
|
Conserved alanine and leucine rich protein.
|
| | | | | | | |
Identified in the membrane fraction of M. tuberculosis H37Rv
|
| | | | | | | |
confers non-target based resistance to azoles,
|
776100
|
mmpL5
|
0.9585
|
ACC
|
794
|
ATC
|
T/I
|
integral component of plasma membrane
|
clofazimine and bedaquiline,
|
| | | | | | | |
via an efflux mechanism.
|
738522
|
mmaA2
|
0.9585
|
GAA
|
213
|
GAC
|
E/D
|
plasma membrane
|
Involved in mycolic acids modification.
|
3530955
|
Rv3161c
|
0.9585
|
GTC
|
62
|
CTC
|
V/L
|
plasma membrane
|
Possible dioxygenase
|
3266030
|
ppsD
|
0.9585
|
TCA
|
1261
|
TCG
|
S/S
|
plasma membrane
|
Phenolpthiocerol synthesis type-I polyketide synthase PpsD
|
262268
|
Rv0219
|
0.9585
|
GCA
|
5
|
GCT
|
A/A
|
Cell wall
|
Probable conserved transmembrane
|
| | | | | | | |
Probable dihydroorotate dehydrogenase PyrD.
|
2399734
|
pyrD
|
0.9585
|
GGC
|
339
|
AGC
|
G/S
|
plasma membrane
|
Essential gene for in vitro growth of H37Rv,
|
| | | | | | | |
by analysis of saturated Himar1 transposon libraries [13]
|
931123
|
lpqQ
|
0.9527
|
TAT
|
57
|
TAC
|
Y/Y
|
extracellular region
|
Possible lipoprotein LpqQ
|
| | | | | | | |
ESX conserved component EccA3.
|
342146
|
eccA3
|
0.9527
|
GAA
|
6
|
GCA
|
E/A
|
plasma membrane
|
ESX-3 type VII secretion system protein.
|
| | | | | | | |
Part of the ESX-3 specialized secretion system.
|
2388641
|
ansP1
|
0.9527
|
GGC
|
9
|
GAC
|
G/D
|
integral component of membrane
|
L-asparagine permease AnsP1
|
2138453
|
Rv1888A
|
0.9527
|
GGG
|
55
|
GGA
|
G/G
|
Cell wall
|
Conserved hypothetical protein
|
213147
|
sigG
|
0.9527
|
GAC
|
332
|
TAC
|
D/Y
|
unknown
|
Probable alternative RNA polymerase sigma factor SigG
|