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Table 1 Clinical features, causative organisms, management and outcomes

From: Outpatient parenteral antimicrobial therapy (OPAT) for aortic vascular graft infection; a five-year retrospective evaluation

Patient No. Age Co-mobidity Index Index device and indication Early complications/ Index device infection features Other surgical history prior to Time Zero (first entry to OPAT) First clinical presentation with infection Leucocytosis at presentation Organism(s) cultured Managment of index device infection No. of OPAT episodes Outcome of most recent OPAT episode (months post presentation with infection, cause of death)
1 84 7 Emergency EVAR for AAA Rupture Bacteraemic at time of EVAR insertion, suspected AEF   Fever No Bacteroides fragilis (blood culture) OPAT, lifelong oral suppresion 1 Failure – RIP (10- pancreatic carcinoma)
2 80 4 Elective EVAR for AAA size Suspected AEF   Fever, abdominal pain No Salmonella enteritidis, Streptococcus anginosis (blood culture, sac aspirate) Sac aspirate, OPAT, lifelong oral suppression 3 Partial success, 45
3 79 5 Emergency EVAR for AAA Rupture + fem-fem bypass graft nNo   Fever, back pain, anorexia, melena No None OPAT, lifelong oral suppression 2 Partial success, 34
4 69 5 Semi-elective EVAR for AAA size + fem-fem bypass graft Endoleak, LRTI post-op Repair of endoleak 3 days after initial surgery Abdominal pain, anorexia No None OPAT, lifelong oral suppression 2 Partial success, 47
5 71 7 Elective EVAR for AAA size Endoleak Repositioning of stent Anorexia, abdominal pain, back pain   CoNS, (sac aspirate) Sac aspirate, OPAT, lifelong oral suppression 1 Failure – RIP (27- severe cardiac failure and cardiogenic shock)
6 81 U Semi-elective EVAR for AAA size, mycotic aneurysm Suspected AEF   Back pain No None OPAT, lifelong oral suppression 1 Success, 25
7 68 4 Elective EVAR for AAA size Fever for 3 days post deployment, no focus found, radiology no collection   Fever Yes None OPAT, oral consolidation 6 months 1 Success, 36
8 75 4 EVAR for AAA size and symptoms Occlusion of right limb of EVAR, suspected AEF   Fever, abdominal/back pain, anorexia, bleeding Yes Enterococcus faecalis, Bacteroides caccae (vertebral biopsy) OPAT, lifelong oral suppression 3 Partial success, 40
9 70 4 Semi-elective EVAR for AAA size and symptoms Right hip pain Ax-fem bypass graft right limb balloon angioplasty sac drainage Anorexia, collection formation Yes Pseudomonas (sac aspirate, blood culture) Multiple debridements and drainage, explant + allograft
OPAT, lifelong oral suppression
3 Partial success, 25
10 81 7 Elective EVAR for symptoms Wound infection post-op Fem-fem bypass graft with development of sinus Fever, back pain, anorexia, cachexia No MSSA, Pseudomonas aeruginosa, anaerobes, CoNS, Enterococcal sp. (VRE) – (sinus swabs/excision) Sinus excision, OPAT, lifelong oral suppression 2 Partial success, 60
11 86 10 Elective EVAR for AAA size No Fem-fem cross over for limb occlusion with development of sinus of fem-fem graft Fever Yes Staphylococcus caprae, candida (excised sinus) Sinus excision, OPAT, lifelong oral suppression 1 Failure – RIP (5 – multilobar pneumonia)
  1. EVAR Endovascular Aortic Anuerysm Repair, AAA Abdominal aortic aneurysm, Fem-fem Femorofemoral bypass grafting, Ax-fem Axillobifemoral bypass grafting, MSSA Methicillin Sensitive Staphylococcus aureus, CoNS Coagulase Negative Staphylococcus, OPAT Outpatient Parenteral Antimicrobial Therapy, RIP Patient dead at time of data analysis