Table 1 Symptom surveillance across organ systems for study participants during longitudinal evaluations and in accordance with biospecimen collections

General

Fever, fatigue, exercise intolerance, weakness, appetite loss, hair loss, night sweats

Neurologic

Headache, dizziness, loss of consciousness, deafness or change in hearing, numbness, tingling, or burning sensation in extremities, loss of taste, loss of smell, change in taste, forgetful or absent minded, confused, difficulty concentrating

Ocular

Eye pain, redness, tearing, light sensitivity, floaters, loss of vision, blurry vision, flashes of light, eye burning

Head and Neck

Sore throat, runny nose, congestion, sinusitis, facial pressure, neck pain, mouth sores

Cardiac

Palpitations, chest pain, lower extremity swelling, chest burning, chest pressure, rapid heart rate

Pulmonary

Difficulty breathing, cough, phlegm in the back of throat, wheezing

Gastrointestinal

Abdominal pain, diarrhea, constipation, nausea, vomiting, reflux

Integumentary

Rash, dry skin, itching, jaundice

Musculoskeletal

Muscle aches, body aches, back pain, joint pain

Reproductive

Erectile dysfunction, amenorrhea, change in menstruation

Hematologic

Easy bruising, bleeding, clot

Psychologic

Anxiety, depression, difficulty sleeping

Other

Patients are asked about other persistent or new symptoms not mentioned above