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Table 2 HRs of death for all, liver-related and non-liver-related causes according to HCV status

From: Hepatitis C virus infection and risk of liver-related and non-liver-related deaths: a population-based cohort study in Naples, southern Italy

HCV status All-cause deathsa (n = 606) Liver-related deaths (n = 56) Non-liver-related deathsa (n = 550)
N (%) HR (95% CI)b AR (95% CI)c N (%) HR (95% CI)b AR (95% CI)c N (%) HR (95% CI)b AR (95% CI)c
Anti-HCV- 452 (10.9) 1d   41 (12.2) 1d   437 (10.5) 1d  
Anti-HCV+ 154 (45.8) 1.38 (1.12 – 1.70) 27.5 (10.7 – 41.2) 3 (3.3) 5.90 (3.00 – 11.59) 83.1 (66.7 – 91.4) 113 (33.6) 1.08 (0.84 – 1.37) 7.4 (-19.0 – 27.0)
 HCV RNA- 31 (34.4) 1.09 (0.77 – 1.54) 8.3 (-29.9 – 35.1) 38 (15.5) 3.05 (0.84 – 11.08) 67.2 (-19.0 – 91.0) 28 (31.1) 1.02 (0.72 – 1.46) 2.0 (-38.9 – 31.5)
 HCV RNA+ 123 (50.0) 1.51 (1.18 – 1.94) 33.8 (15.3 – 48.5) 41 (12.2) 6.61 (3.29 – 13.27) 84.9 (69.6 – 92.5) 85 (34.6) 1.11 (0.82 – 1.49) 9.1 (-22.0 – 32.9)
  1. Abbreviations: AR attributable risk, CI confidence interval, eGFR Estimated Glomerular Filtration Rate, HR hazard ratio
  2. aNon-natural causes of death (ICD-10 codes: S00-T98) excluded; bEstimated using Fine-Gray models adjusted for sex, age at enrolment, years of education, HBsAg status, presence of hyperglycaemia (fasting plasma glucose > 126 mg/dL) or reduced kidney function (eGFR< 60 mL/min/1.73m2), and FIB-4 index score; cCalculated from the adjusted Fine-Gray models; dReference category