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Table 2 HRs of death for all, liver-related and non-liver-related causes according to HCV status

From: Hepatitis C virus infection and risk of liver-related and non-liver-related deaths: a population-based cohort study in Naples, southern Italy

HCV status

All-cause deathsa (n = 606)

Liver-related deaths (n = 56)

Non-liver-related deathsa (n = 550)

N (%)

HR (95% CI)b

AR (95% CI)c

N (%)

HR (95% CI)b

AR (95% CI)c

N (%)

HR (95% CI)b

AR (95% CI)c

Anti-HCV-

452 (10.9)

1d

 

41 (12.2)

1d

 

437 (10.5)

1d

 

Anti-HCV+

154 (45.8)

1.38 (1.12 – 1.70)

27.5 (10.7 – 41.2)

3 (3.3)

5.90 (3.00 – 11.59)

83.1 (66.7 – 91.4)

113 (33.6)

1.08 (0.84 – 1.37)

7.4 (-19.0 – 27.0)

 HCV RNA-

31 (34.4)

1.09 (0.77 – 1.54)

8.3 (-29.9 – 35.1)

38 (15.5)

3.05 (0.84 – 11.08)

67.2 (-19.0 – 91.0)

28 (31.1)

1.02 (0.72 – 1.46)

2.0 (-38.9 – 31.5)

 HCV RNA+

123 (50.0)

1.51 (1.18 – 1.94)

33.8 (15.3 – 48.5)

41 (12.2)

6.61 (3.29 – 13.27)

84.9 (69.6 – 92.5)

85 (34.6)

1.11 (0.82 – 1.49)

9.1 (-22.0 – 32.9)

  1. Abbreviations: AR attributable risk, CI confidence interval, eGFR Estimated Glomerular Filtration Rate, HR hazard ratio
  2. aNon-natural causes of death (ICD-10 codes: S00-T98) excluded; bEstimated using Fine-Gray models adjusted for sex, age at enrolment, years of education, HBsAg status, presence of hyperglycaemia (fasting plasma glucose > 126 mg/dL) or reduced kidney function (eGFR< 60 mL/min/1.73m2), and FIB-4 index score; cCalculated from the adjusted Fine-Gray models; dReference category