Table 2 Comparison of severity and radiological characteristics in both training and test cohort
radiological characteristics | Training cohort | p value | Test cohort | p value | p value* | ||
|---|---|---|---|---|---|---|---|
Non-severe (n = 77) | Severe (n = 28) | Non-severe (n = 33) | Severe (n = 12) | ||||
Number of lesions | 11.7 ± 7.9 | 21.8 ± 10.1 | < 0.001 | 11.6 ± 8.5 | 18.6 ± 6.6 | 0.009 | 0.576 |
CT score | < 0.001 | < 0.001 | 0.982 | ||||
1 | 20 (26.0) | 0 (0.0) | 9 (27.3) | 0 (0.0) | |||
2 | 20 (26.0) | 0 (0.0) | 8 (24.2) | 0 (0.0) | |||
3 | 21 (27.3) | 2 (7.1) | 10 (30.3) | 1 (8.3) | |||
4 | 16 (20.8) | 26 (92.9) | 6 (18.2) | 11 (91.7) | |||
Distribution of lesions | 0.085 | 0.450 | 0.767 | ||||
Left lung | 4 (5.2) | 0 (0.0) | 2 (6.1) | 0 (0.0) | |||
Right lung | 8 (10.4) | 0 (0.0) | 2 (6.1) | 0 (0.0) | |||
Both lungs | 65 (84.4) | 28 (100.0) | 29 (87.9) | 12 (100.0) | |||
Pure GGO | 0.445 | 0.669 | 0.999 | ||||
Absence | 8 (13.4) | 5 (17.9) | 4 (13.2) | 2 (16.7) | |||
Presence | 69 (89.6) | 23 (82.1) | 29 (87.8) | 10 (83.3) | |||
Consolidation | 0.213 | 0.204 | 0.999 | ||||
Absence | 61 (79.2) | 28 (100.0) | 26 (78.8) | 12 (100.0) | |||
Presence | 16 (20.8) | 0 (0.0) | 7 (21.2) | 0 (0.0) | |||
GGO with consolidation | 0.013 | 0.027 | 0.482 | ||||
Absence | 22 (28.6) | 1 (3.6) | 13 (39.4) | 0 (0.0) | |||
Presence | 55 (71.4) | 27 (96.4) | 20 (60.6) | 12 (100.0) | |||
Crazy-paving pattern | 0.005 | 0.344 | 0.089 | ||||
Absence | 36 (46.8) | 4 (14.3) | 9 (27.3) | 1 (8.3) | |||
Presence | 41 (53.2) | 24 (85.7) | 24 (72.7) | 11 (91.7) | |||
Halo sign | 0.012 | 0.228 | 0.823 | ||||
Absence | 11 (14.3) | 11 (39.3) | 4 (12.1) | 4 (33.3) | |||
Presence | 66 (85.7) | 17 (60.7) | 29 (87.9) | 8 (66.7) | |||
Reversed halo sign | 0.861 | 0.576 | 0.999 | ||||
Absence | 63 (81.8) | 24 (85.7) | 26 (78.8) | 11 (91.7) | |||
Presence | 14 (18.2) | 4 (14.3) | 7 (21.2) | 1 (8.3) | |||
Interlobular septal thickening | 0.072 | 0.109 | 0.148 | ||||
Absence | 30 (39.0) | 5 (17.9) | 9 (27.3) | 0 (0.0) | |||
Presence | 47 (61.0) | 23 (82.1) | 24 (72.7) | 12 (100.0) | |||
Air bronchogram | 0.087 | 0.344 | 0.546 | ||||
Absence | 26 (33.8) | 4 (14.3) | 9 (27.3) | 1 (8.3) | |||
Presence | 51 (66.2) | 24 (85.7) | 24 (72.7) | 11 (91.7) | |||
Pleura effusion | 0.999 | 0.593 | 0.999 | ||||
Absence | 74 (96.1) | 27 (96.4) | 33 (100.0) | 11 (91.7) | |||
Presence | 3 (3.9) | 1 (3.6) | 0 (0.0) | 1 (8.3) | |||
Rad-scorea | −3.5 (−4.2, −1.9) | 1.2 (0.3, 2.1) | < 0.001 | −2.9 [−3.7, −1.7] | −0.1 (−1.2, 1.5) | < 0.001 | 0.613 |