Table 1 Comparison of severity and clinical characteristics in both training and test cohort
Clinical characteristics | Training cohort | p value | Test cohort | p value | p value* | ||
|---|---|---|---|---|---|---|---|
Non-severe (n = 77) | Severe (n = 28) | Non-severe (n = 33) | Severe (n = 12) | ||||
Age | 43.4 ± 14.6 | 55.6 ± 12.6 | < 0.001 | 43.4 ± 12.4 | 59.9 ± 19.8) | 0.001 | 0.674 |
Gender | 0.828 | ||||||
Male | 34 (44.2) | 9 (32.1) | 0.377 | 16 (48.5) | 9 (75.0) | 0.214 | |
Female | 43 (55.8) | 19 (67.9) | 17 (51.5) | 3 (25.0) | |||
Fever | 0.999 (86.2%) | 0.269 | 0.439 | ||||
Absence | 9 (11.6%) | 3 (10.7%) | 5 (15.2%) | 1 (8.3%) | |||
Presence | 72 (86.7%) | 22 (88.0%) | 28 (84.8%) | 11 (91.7%) | |||
Cough | 0.054 | 0.999 | 0.521 | ||||
Absence | 43 (55.8) | 9 (32.1) | 14 (42.4) | 5 (41.7) | |||
Presence | 34 (44.2) | 19 (67.9) | 19 (57.6) | 7 (58.3) | |||
C-reaction protein | 0.447 | 0.448 | 0.853 | ||||
Absence | 15 (19.5) | 3 (10.7) | 8 (24.2) | 1 (8.3) | |||
Presence | 62 (80.5) | 25 (89.3) | 25 (75.8) | 11 (91.7) | |||
Blood leukocyte count | 0.088 | 0.999 | 0.805 | ||||
< 4 × 109/L | 26 (33.8) | 16 (57.1) | 21 (63.6) | 6 (50.0) | |||
(4–10) × 109/L | 50 (64.9) | 12 (42.9) | 12 (36.4) | 6 (50.0) | |||
> 10 × 109/L | 1 (1.3) | 0 (0.0) | 0 (0.0) | 0 (0.0) | |||
Lymphocyte count (< 1.5 × 109/L) | 31 (40.3) | 7 (25.0) | 0.227 | 13 (39.4) | 1 (8.3) | 0.104 | 0.680 |
Comorbidity | < 0.001 | 0.228 | 0.103 | ||||
Absence | 61 (79.2) | 10 (35.7) | 29 (87.9) | 8 (66.7) | |||
Presence | 16 (20.8) | 18 (64.3) | 4 (12.1) | 4 (33.3) | |||
Time course (day) | 6.8 ± 3.8 | 9.0 ± 4.9 | 0.016 | 6.8 ± 4.0 | 5.5 ± 3.9 | 0.345 | 0.209 |