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Table 1 Comparison of severity and clinical characteristics in both training and test cohort

From: A novel CT-based radiomics in the distinction of severity of coronavirus disease 2019 (COVID-19) pneumonia

Clinical characteristics Training cohort p value Test cohort p value p value*
Non-severe (n = 77) Severe (n = 28)   Non-severe (n = 33) Severe (n = 12)   
Age 43.4 ± 14.6 55.6 ± 12.6 <  0.001 43.4 ± 12.4 59.9 ± 19.8) 0.001 0.674
Gender        0.828
 Male 34 (44.2) 9 (32.1) 0.377 16 (48.5) 9 (75.0) 0.214  
 Female 43 (55.8) 19 (67.9)   17 (51.5) 3 (25.0)   
Fever    0.999 (86.2%)    0.269 0.439
 Absence 9 (11.6%) 3 (10.7%)   5 (15.2%) 1 (8.3%)   
 Presence 72 (86.7%) 22 (88.0%)   28 (84.8%) 11 (91.7%)   
Cough    0.054    0.999 0.521
 Absence 43 (55.8) 9 (32.1)   14 (42.4) 5 (41.7)   
 Presence 34 (44.2) 19 (67.9)   19 (57.6) 7 (58.3)   
C-reaction protein    0.447    0.448 0.853
 Absence 15 (19.5) 3 (10.7)   8 (24.2) 1 (8.3)   
 Presence 62 (80.5) 25 (89.3)   25 (75.8) 11 (91.7)   
Blood leukocyte count    0.088    0.999 0.805
 < 4 × 109/L 26 (33.8) 16 (57.1)   21 (63.6) 6 (50.0)   
 (4–10) × 109/L 50 (64.9) 12 (42.9)   12 (36.4) 6 (50.0)   
 > 10 × 109/L 1 (1.3) 0 (0.0)   0 (0.0) 0 (0.0)   
Lymphocyte count (< 1.5 × 109/L) 31 (40.3) 7 (25.0) 0.227 13 (39.4) 1 (8.3) 0.104 0.680
Comorbidity    <  0.001    0.228 0.103
 Absence 61 (79.2) 10 (35.7)   29 (87.9) 8 (66.7)   
 Presence 16 (20.8) 18 (64.3)   4 (12.1) 4 (33.3)   
Time course (day) 6.8 ± 3.8 9.0 ± 4.9 0.016 6.8 ± 4.0 5.5 ± 3.9 0.345 0.209
  1. *Represents the comparisons of features between training and test cohorts