Management of enterococcal central line-associated bloodstream infections in patients with cancer

BMC Infectious Diseases

Table 2 Effect of catheter amangement in different groups

1) CLABSI with MBI
Outcome	Catheter removal ^a,b			p-value	Pairwise comparisons with significant differences
	< 3 Days	3–7 Days	> 7 Days ^c
	(n = 23)	(n = 27)	(n = 60)
	N (%)	N (%)	N (%)
Final outcome ^{d, e}				0.004	“3–7 days” vs “> 7 days”: P = .003
Success	18 (78)	18 (67)	56 (93)
Failure	5 (22)	9 (33)	4 (7)
2) CRBSI or CLABSI without MBI
Outcome	Catheter removal ^{a, b}			p-value	Pairwise comparisons with significant differences
	< 3 Days	3–7 Days	> 7 Days ^c
	(n = 24)	(n = 19)	(n = 37)
	N (%)	N (%)	N (%)
Final outcome ^{d, e}				0.025	None (due to alpha adjustment for multiple comparisons)
Success	21 (88)	12 (63)	34 (92)
Failure	3 (13)	7 (37)	3 (8)
3) Non-CLABSI
Outcome	Catheter removal ^{a, b}			p-value	Pairwise comparisons with significant differences
	< 3 Days	3–7 Days	> 7 Days ^c
	(n = 22)	(n = 19)	(n = 88)
	N (%)	N (%)	N (%)
Final outcome ^{d, e}				0.006	“< 3 days” vs “> 7 days”: P = .006
Success	14 (64)	14 (74)	79 (90)
Failure	8 (36)	5 (26)	9 (10)

Abbreviations: CLABSI central line-associated bloodstream infection, MBI mucosal barrier injury
^a Since positve blood culture
^b Patients with lock therapy were excluded from the analysis
^c Included patietns with catheter retained
^d This is a composite outcome. Success means that a patient had no infection-related complication and no infection-related death within 3 months after bacteremia, as well as no infection-related recurrence within 3 months after microbiological resolution
^e Patients who had no microbiological resoltuion, or who had missing data for infecton-related complication, or infection-related death, or recurrence, or who died within 7 days after bacteremia were excluded from the analysis

ISSN: 1471-2334