Risk factors and biofilm formation analyses of hospital-acquired infection of Candida pelliculosa in a neonatal intensive care unit

Table 1 Univariate analyses of factors associated with C. pelliculosa fungemia

Factor	Fungemia	No fungemia	χ2/t/Z	P
Sex			0.015	0.904
Male	13	81
Female	8	47
Age admitted in hospital (day)	1(1,1)	1(1,1)	0.741	0.642
Ward			1.014	0.314
Neonatal ward 1	9	70
Neonatal ward 2	12	58
Age of the mother (year)			9.826	0.007
≥ 35	13	39
30–34	7	49
≤ 29	1	40
Gestational age (WK)			28.837	< 0.001
≥ 36	0	27
30–35	6	83
≤ 29	15	18
PBRP			1.961	0.744
PRM	3	31
PHSP	7	35
Gestational diabetes	0	3
Twins preterm birth	3	11
Other	8	48
Type of delivery			0.121	0.728
Cesarean	15	96
Natural labor	6	32
Birth weight			35.849	< 0.001
ELBW (≤1000 g)	8	4
VLBW (> 1000 g, ≤1500 g)	11	32
LBW (> 1500, ≤2500 g)	1	60
NBW (> 2500)	1	32
Apgar (1 min)			27.137	< 0.001
≥ 7	6	105
< 7	15	23
Apgar (5 min)			0.000	1.000
≥ 7	21	125
< 7	0	3
Glucose at admitted (mmol/l)	4.076 ± 1.685	3.681 ± 1.175	−1.567	0.119
PICC			71.406	< 0.001
No	0	111
Yes	21	17
Endotracheal tube			22.252	< 0.001
No	0	71
Yes	21	57
Nasogastric tube			1.781	0.182
No	0	16
Yes	21	112
Parenteral nutrition (lipid solution)			8.667	0.003
No	0	39
Yes	21	89
PCBI			1.454	0.228
No	20	105
Yes	1	23
BSAU			17.421	< 0.001
No	0	62
Yes	21	66
TBSA			4.582	0.032
No	15	116
Yes	6	12
Surgical procedure			0.000	1.000
No	20	121
Yes	1	7
Time hospitalization	59.790 ± 21.423	25.190 ± 16.185	−10.146	< 0.001

PBRP premature birth related problems, PRM Premature rupture of membranes, PHSP pregnancy-induced hypertension syndrome or preeclampsia, ELBW extremely low birth weight, VLBW very low birth weight, LBW low birth weight, NBW normal birth weight, PICC peripherally inserted central catheter, PCBI previous or concomitant bacteremic infection, BSAU broad-spectrum antibiotics use before fungemia, TBSA three or more broad-spectrum antimicrobials

ISSN: 1471-2334