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Table 3 Laboratory results of patients with COVID-19 on hospital admission

From: Associated risk factors with disease severity and antiviral drug therapy in patients with COVID-19

Variables All Patients (n = 550) Severe (n = 178) Non-severe (n = 372) p value
Blood tests, n/total n (%)
 Leucocytes (×109/L)
   < 4 119/502(23.7%) 21/169(12.4%) 98/333(29.4%) < 0.001
  4–10 335/502(66.7%) 110/169(65.1%) 225/333(67.6%) < 0.001
   > 10 48/502(9.6%) 38/169(22.5%) 10/333(3.0%) < 0.001
 Neutrophil percentage (%)
  40–75 321/502(63.9%) 47/169(27.8%) 274/333(82.3%) < 0.001
   > 75 175/502(34.9%) 122/169(72.2%) 53/333(15.9%) < 0.001
 Lymphocyte percentage (%)
   < 20 230/502(45.8%) 143/169(84.6%) 87/333(26.1%) < 0.001
  20–50 267/502(53.2%) 26/169(15.4%) 241/333(72.4%) < 0.001
 Lymphocytes (×109/L)
   < 1.0 250/502(49.8%) 130/169(76.9%) 120/333(36.0%) < 0.001
   ≥ 1.0 252/502(50.2%) 39/169(23.1%) 213/333(64.0%) < 0.001
 Hemoglobin (g/L)
  Normal 317/502(63.1%) 108/169(63.9%) 209/333(62.8%) 0.802
  Decreased 185/502(36.9%) 61/169(36.1%) 124/333(37.2%) 0.802
 Platelets (×109/L)
   < 100 34/502(6.8%) 13/169(7.7%) 21/333(6.3%) 0.559
   ≥ 100 468/502(93.2%) 156/169(92.3%) 312/333(93.7%) 0.559
Inflammatory parameters-no./total no. (%)
 Procalcitonin (ng/ml)
   ≤ 0.1 279/393(71.0%) 63/149(42.3%) 216/244(88.5%) < 0.001
   > 0.1 117/393(29.0%) 86/149(57.7%) 28/244(11.5%) < 0.001
 hsCRP (mg/L)
   ≤ 3 120/404(29.7%) 5/136(3.7%) 115/268(42.9%) < 0.001
   > 3 284/404(70.3%) 131/136(96.3%) 153/268(57.1%) < 0.001
 ESR (mm/h)
   ≤ 15 74/185(40.0%) 3/55(5.5%) 71/130(54.6%) < 0.001
   > 15 111/185(60.0%) 52/55(94.5%) 59/130(45.4%) < 0.001
Myocardial enzyme-no./total no. (%)
 CK-MB (ng/mL)
   ≤ 6.22 399/422(94.5%) 130/146(89.0%) 269/276(97.5%) < 0.001
   > 6.22 23/422(5.5%) 16/146(11.0%) 7/276(2.5%) < 0.001
 Troponin T (ng/ml)
   ≤ 0.014 331/438(75.6%) 82/161(50.9%) 249/277(89.9%) < 0.001
   > 0.014 107/438(24.4%) 79/161(49.1%) 28/277(10.1%) < 0.001
Heart Failure Indicator-no./total no. (%)
 BNP (pg/ml)
   ≤ 222 166/291(57.0%) 43/128(33.6%) 123/163(75.5%) < 0.001
   > 222 125/291(43.0%) 85/128(66.4%) 40/163(24.5%) < 0.001
Liver function-no./total no. (%)
 Alanine transaminase (IU/L)
   ≤ 50 443/511(86.7%) 136/175(77.7%) 307/336(91.4%) < 0.001
   > 50 68/511(13.3%) 39/175(22.3%) 29/336(8.6%) < 0.001
 Aspartate aminotransferase (IU/L)
   ≤ 40 393/511(76.9%) 95/175(54.3%) 298/336(88.7%) < 0.001
   > 40 118/511(23.1%) 80/175(45.7%) 38/336(11.3%) < 0.001
 Albumin (g/L)
   < 40 345/511(67.5%) 163/175(93.1%) 182/336(54.2%) < 0.001
  40–55 166/511(32.5%) 12/175(6.9%) 154/336(45.8%) < 0.001
Coagulation Function, n/total n (%)
 APTT (S)
  24.6–35.4 364/430(84.7%) 136/158(86.1%) 228/272(83.8%) 0.532
   > 35.4 66/430(15.3%) 22/158(13.9%) 44/272(16.2%) 0.532
 D-dimer (μg/ml)
   ≤ 0.243 182/364(50.0%) 25/133(18.8%) 157/231(68.0%) < 0.001
   > 0.243 182/364(50.0%) 108/133(81.2%) 74/231(32.0%) < 0.001
Electrolyte, n/total n (%)
 Potassium (mmol/L)
   > 5.3 39/504(7.7%) 22/172(12.8%) 17/332(5.1%) < 0.001
  3.5–5.3 389/504(77.2%) 109/172(63.4%) 280/332(84.4%) < 0.001
   < 3.5 76/504(15.1%) 41/172(23.8%) 35/332(10.5%) < 0.001
 Sodium (mmol/L)
   < 137 72/504(14.3%) 44/172(25.6%) 28/332(8.4%) < 0.001
  137–147 411/504(81.5%) 115/172(66.8%) 296/332(89.2%) < 0.001
   > 147 21/504(4.2%) 13/172(7.6%) 8/332(2.4%) < 0.001
Renal Function, n/total n (%)
 Creatinine (μmol/L)
   ≤ 111 480/508(94.5%) 160/176(90.9%) 320/332(96.4%) 0.010
   > 111 28/508(5.5%) 16/176(9.1%) 12/332(3.6%) 0.010
 GFR
   < 66 36/508(7.1%) 24/176(13.6%) 12/332(3.6%) < 0.001
   ≥ 66 472/508(92.9%) 152/176(86.4%) 320/332(96.4%) < 0.001
Arterial blood gas analysis, n/total n (%)
 PH
   < 7.35 23/338(6.8%) 14/165(8.5%) 9/173(5.2%) < 0.001
  7.35–7.45 233/338(68.9%) 90/165(54.5%) 143/173(82.7%) < 0.001
   > 7.45 82/338(24.3%) 61/165(37.0%) 21/173(12.1%) < 0.001
 Oxygenation index
   < 100 26/338(7.7%) 26/165(15.8%) 0/173(0.0%) < 0.001
  100–300 98/338(29.0%) 98/165(59.4%) 0/173(0.0%) < 0.001
   > 300 214/338(63.3%) 41/165(24.8%) 173/173(100.0%) < 0.001
 PCO2 (mmHg)
   < 35 73/338(21.6%) 52/165(31.5%) 21/173(12.1%) < 0.001
  35–45 185/338(54.7%) 90/165(54.6%) 95/173(55.0%) < 0.001
   > 45 80/338(23.7%) 23/165(13.9%) 57/173(32.9%) < 0.001
 Lactic acid (mmol/L)
   ≤ 2.2 245/338(72.5%) 114/165(69.1%) 131/173(75.7%) 0.172
   > 2.2 93/338(27.5%) 51/165(30.9%) 42/173(24.3%) 0.172
  1. The data were expressed in the form of n/N (%), where N represents the total number of patients with available data
  2. hsCRP Hypersensitive c-reactive protein, ESR Erythrocyte sedimentation rate, CKMB Creatine kinase isoenzyme, BNP B-type natriuretic peptide, APTT Activated partial thromboplastin time, GFR Glomerular filtration rate, PCO2 Partial pressure of carbon dioxide