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Table 1 The characteristics and immunological profiles of the patients with and without antibody response

From: Immune cell profiling and antibody responses in patients with COVID-19

Variables IgM antibody   IgG antibody  
Non-responders (n = 14) Median (IQR) Responders (n = 39)
Median (IQR)
P value Non-responders (n = 13) Median (IQR) Responders (n = 40)
Median (IQR)
P value
Age (year) 54 (33–68) 54 (39–60) 0. 82 59 (42–76) 53 (39–60) 0.94
Days after onset of symptom 9 (5–13) 14 (11–18) 0.036 10 (6–14) 14 (10–18) 0.23
Erythrocyte sedimentation rate (mm/h) 35 (25–72) 48 (35–69) 0.49 36 (26–73) 48 (34–69) 0.45
C-reactive protein (mg/L) 18 (14–40) 31.5 (19–42) 0.22 17 (7–34) 31.5 (19–41) 0.18
Interleukin 6 (pg/mL) 11.3 (8–15) 10 (6–16) 0.2 11 (8–15) 10 (6–16) 0.32
White blood cell count (× 106 cells / L) 10,980 (6928–15,000) 7030 (5220–9980) 0.1 10,860 (7150–17,075) 7000 (5230–1024) 0.17
Neutrophil count (× 106 cells / L) 6865 (5498–10,691) 4370 (2871–660) 0.024 7700 (5259–11,625) 4284 (2659–6840) 0.046
Lymphocyte count (× 106 cells / L) 1878 (1160–2344) 1681 (1320–2000) 0.3 1776 (1042–2098) 1715 (1320–2131) 0.47
Total T cell counts (CD3+) 1148 (627–1465) 1003 (739–1370) 0.69 1019 (391–1305) 1100.5 (785–1412) 0.94
CD4+ T cell counts 685.5 (283–872) 663 (399–876) 0.82 580 (249–787) 693.5 (463–902) 0.23
CD8+ T cell counts 343 (216–449) 280 (180–420) 0.3 294 (117–451) 291 (193–417) 0.93
B cells (CD19+) counts 230 (125–418) 164.5 (105–237) 0.35 195.5 (107–303) 171.5 (110–243) 0.74
B cells (CD20+) counts 227.5 (126–398) 159.5 (104–234) 0.12 200 (109–288) 165 (109–242) 0.74
NK cell counts 136 (79–318) 151 (127–263) 0.95 135 (68–244) 158.5 (130–282) 0.69
Neutrophil to lymphocyte ratio 4.6 (2.2–9.6) 2.4 (1.2–4.1) 0.31 4.8 (2.5–9.9) 2.3 (1.3–4.1) 0.17
  1. Data were presented as the median (interquartile range) and were analyzed using the Mann–Whitney test. IgM, immunoglobulin M; IgG, immunoglobulin G; NK, natural killer. p value < 0.05 was considered statistically significant