Biological samples | Study population | Laboratory testing |
---|---|---|
Whole blood | Febrile cases | Blood culture |
 | Cases/ healthy controls | Molecular detection of bacteria (FTD® Bacterial pneumonia CAP) for RTI cases |
 | Cases/ healthy controls | Molecular detection of viruses and bacteria (multiplex PCR-based macroarray assay) for AFDUC cases and RTI/GI cases without first-line pathogen detection |
Naso−/ Oropharyngeal swabs | Cases/ healthy controls | Molecular detection of viruses and bacteria (FTD® respiratory pathogens 33) |
 | Cases | Molecular detection of SARS-CoV-2 (TIB Molbiol LightMix® SarbecoV E-gene and SARS-CoV-2 RdRP-gene) from March 2020 onwards, and retrospectively from December 2019 on |
Stool | Cases | Stool culture |
 | Cases/ healthy controls | Molecular detection of viruses (FTD® viral gastroenteritis), bacteria (FTD® bacterial gastroenteritis) and parasites (FTD® stool parasites) |