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Table 3 Comparison between two subgroups of the multicentric lesion group

From: Human papillomavirus genotypes and the risk factors associated with multicentric intraepithelial lesions of the lower genital tract: a retrospective study

   Low-grade lesions group, n = 208 (%) High-grade lesions group, n = 97, (%) OR(95% CI)
Age, median (Q1-Q3)   50 (43–56) 50 (41.5–55)  
The grade of vaginal and/or vulval lesion, n (%) VAIN1/VIN1 111(53.4) 28(28.9) 2.82 (1.68–4.73)
VAIN2–3/VIN2 97(46.6) 69(71.1)  
HPV test, n (%) Positive 198(95.7) 94(100) NA
Negative 9(4.3) 0  
Multiple HPV infection, n (%) Yes 43(37.1) 20(33.3) 0.85 (0.44–1.64)
No 73(62.9) 40(66.7)  
HR-HPV viral load, n (%) >1000 19(26.8) 8(27.6) 0.96 (0.36–2.53)
≤1000 52(73.2) 21(72.4)  
No. of patients with available HPV genotype results, n   115 60  
HR-HPV genotype, n (%) 16 36(31.3) a 32(53.3) 2.54 (1.34–4.83)
18 8(7.0) 7(11.7) 1.78 (0.61–5.28)
  Non 16/18 genotypes 72(62.6) 21(35.0) 3.04 (1.59–5.82)
  1. a one patient had both HPV16 and HPV18 infection
  2. HPV human papillomavirus, HR-HPV high-risk human papillomavirus, OR odds ratio, CI confidence interval