| | |
Low-grade lesions group, n = 208 (%)
|
High-grade lesions group, n = 97, (%)
|
OR(95% CI)
|
|---|
|
Age, median (Q1-Q3)
| |
50 (43–56)
|
50 (41.5–55)
| |
|
The grade of vaginal and/or vulval lesion, n (%)
|
VAIN1/VIN1
|
111(53.4)
|
28(28.9)
|
2.82 (1.68–4.73)
|
|
VAIN2–3/VIN2
|
97(46.6)
|
69(71.1)
| |
|
HPV test, n (%)
|
Positive
|
198(95.7)
|
94(100)
|
NA
|
|
Negative
|
9(4.3)
|
0
| |
|
Multiple HPV infection, n (%)
|
Yes
|
43(37.1)
|
20(33.3)
|
0.85 (0.44–1.64)
|
|
No
|
73(62.9)
|
40(66.7)
| |
|
HR-HPV viral load, n (%)
|
>1000
|
19(26.8)
|
8(27.6)
|
0.96 (0.36–2.53)
|
|
≤1000
|
52(73.2)
|
21(72.4)
| |
|
No. of patients with available HPV genotype results, n
| |
115
|
60
| |
|
HR-HPV genotype, n (%)
|
16
|
36(31.3) a
|
32(53.3)
|
2.54 (1.34–4.83)
|
|
18
|
8(7.0)
|
7(11.7)
|
1.78 (0.61–5.28)
|
| |
Non 16/18 genotypes
|
72(62.6)
|
21(35.0)
|
3.04 (1.59–5.82)
|
- a one patient had both HPV16 and HPV18 infection
- HPV human papillomavirus, HR-HPV high-risk human papillomavirus, OR odds ratio, CI confidence interval
