Table 3 Comparison between two subgroups of the multicentric lesion group
Low-grade lesions group, n = 208 (%) | High-grade lesions group, n = 97, (%) | OR(95% CI) | ||
|---|---|---|---|---|
Age, median (Q1-Q3) | 50 (43–56) | 50 (41.5–55) | ||
The grade of vaginal and/or vulval lesion, n (%) | VAIN1/VIN1 | 111(53.4) | 28(28.9) | 2.82 (1.68–4.73) |
VAIN2–3/VIN2 | 97(46.6) | 69(71.1) | ||
HPV test, n (%) | Positive | 198(95.7) | 94(100) | NA |
Negative | 9(4.3) | 0 | ||
Multiple HPV infection, n (%) | Yes | 43(37.1) | 20(33.3) | 0.85 (0.44–1.64) |
No | 73(62.9) | 40(66.7) | ||
HR-HPV viral load, n (%) | >1000 | 19(26.8) | 8(27.6) | 0.96 (0.36–2.53) |
≤1000 | 52(73.2) | 21(72.4) | ||
No. of patients with available HPV genotype results, n | 115 | 60 | ||
HR-HPV genotype, n (%) | 16 | 36(31.3) a | 32(53.3) | 2.54 (1.34–4.83) |
18 | 8(7.0) | 7(11.7) | 1.78 (0.61–5.28) | |
Non 16/18 genotypes | 72(62.6) | 21(35.0) | 3.04 (1.59–5.82) |