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Table 1 The demographics and clinical characteristic of TM bloodstream infection AIDS patients

From: Clinical characteristics and risk factors for poor prognosis among HIV patients with Talaromyces marneffei bloodstream infection

Demographics and clinical data

Normal range

Total cases (n = 87)

Survival cases (n = 72)

Poor prognosis (n = 15)

P-value

Age (years)

–

34.0 (28.0--44.0)

33.5 (27.3--43.0)

37.0 (30.0—46.0)

0.71

Male (%)

–

81 (93%)

68 (94%)

13 (87%)

0.28*

WBC (*10^9/L)

3.5 ~ 9.5

3.4 (2.4--5.1)

3.4 (2.4--4.9)

4.5 (2.1—8.1)

0.57

Neutrophil (*10^9/L)

1.8 ~ 6.3

2.9 (1.7--4.2)

2.9 (1.7--4.0)

2.4 (1.6—6.5)

0.65

Hemoglobin (g/L)

115 ~ 150

94 (81--107)

95 (81--107)

86 (80—104)

0.30

Platelet (*10^9/L)

125 ~ 350

100 (66--155)

99.5 (72.3--149.3)

103 (23—198)

0.60

CD4 count (/ul)

410 ~ 1590

7 (4--19)

N† = 84

9 (4--21)

N† = 71

5 (3—12)

N† = 13

0.05

CD8 count (/ul)

190 ~ 1140

202 (98--336) N = 82

223 (106--384)

N = 70

122 (57—186)

N = 12

0.01

Ratio of CD4/CD8

0.9 ~ 3.6

0.04 (0.02--0.10) N = 82

0.04 (0.02--0.10)

N = 70

0.06 (0.03—0.10)

N = 12

0.74

BUN (mmol/L)

2.6 ~ 7.5

4.1 (3.2--6.0) N = 86

4.0 (3.1--5.4)

N = 72

6.6 (4.0—12.2)

N = 14

0.001

Serum Albumin (g/L)

40 ~ 55

27 (23--31)

N = 86

28 (24--31)

N = 72

25 (22—28)

N = 14

0.07

PCT (ng/mL)

0 ~ 0.05

0.63 (0.21--1.75) N = 74

0.50 (0.19--1.65) N = 63

1.09 (0.62—15.45) N = 11

0.04

CRP (mg/L)

0 ~ 10

54 (26--88)

N = 76

44 (24--81)

N = 63

71 (53—111)

N = 13

0.03

BDG (pg/mL)

< 60

194 (48--264) N = 74

205 (101--287)

N = 62

54 (10—222)

N = 12

0.01

Fever

–

81 (93.1%)

67 (93.1%)

14 (93.3%)

0.97*

Rash

–

31 (35.6%)

26 (36.1%)

5 (33.3%)

0.84*

Lymphnode enlargement

–

25 (28.7%)

21 (29.2%)

4 (26.7%)

0.85*

TB coinfection

–

5 (5.7%)

5(6.9%)

0(0%)

0.29*

NTM disease

–

10(11.5%)

9 (12.5%)

1 (6.7%)

0.52*

CMVR

–

8 (9.2%)

8 (11.1%)

0 (0%)

0.18*

PCP

–

10 (11.5%)

8(11.1%)

2 (13.3%)

0.81*

Cryptococcal meningitis

–

1 (1.1%)

1 (1.4%)

0(0%)

0.65*

Oral candidiasis

–

9 (10.3%)

5 (6.9%)

4 (26.7%)

0.02*

Hospital stay (days)

–

21 (16–25)

22 (19–26)

5 (3–13)

< 0.0001

Culture turnaround (days)

–

8 (6--9)

8 (6--9)

6 (5--9)

0.12

  1. * By Fisher exact test; Others by Mann-Whitney test; †N, means some of the cases with the clinical data and being collected in this analysis. WBC white blood cell; BUN blood urea nitrogen; PCT procalcitonin; CRP C-reactive protein; BDG 1,3-β-D-Glucose; TB tuberculosis; NTM Nontuberculous mycobacteria; CMVR Cytomegalovirus rentinitis; PCP Pneumocystis jirovecii pueumonia