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Table 4 Factors associated with LJ colony count during the first two months of treatment

From: Baseline Xpert MTB/RIF ct values predict sputum conversion during the intensive phase of anti-TB treatment in HIV infected patients in Kampala, Uganda: a retrospective study

Variable

Unadjusted

Adjusted

OR (95% CI)

P-value

OR (95% CI)

P-value

Baseline ct valuea

 Week 0

0.91 (0.88  ̶ 0.94)

<  0.001

0.84 (0.76  ̶ 0.92)

<  0.001

 Week 2

0.84 (0.76  ̶ 0.92)

 < 0.001

0.86 (0.79  ̶ 0.95)

    0.002

 Week 4

0.83 (0.72  ̶ 0.95)

    0.007

0.86 (0.75  ̶ 0.98)

    0.026

 Week 6

0.86 (0.73  ̶ 1.00)

    0.057

0.89 (0.76  ̶ 1.04)

    0.139

 Week 8

0.88 (0.73  ̶ 1.06)

    0.167

0.91 (0.75  ̶ 1.09)

    0.302

Cavitation

 No

Ref

   

 Yes

2.54 (1.56  ̶ 4.13)

<  0.001

3.56 (1.33  ̶ 9.54)

   0.012

CD4 cell count

  ≤ 200 cells/μL

Ref

   

  > 200 cells/μL

0.59 (0.38  ̶ 0.92)

   0.020

0.86 (0.63 –1.17)

   0.073

ART status

 On ART

Ref

   

 Not on ART

0.92 (0.54  ̶ 1.57)

  0.758

  

Body Mass Index

  ≤ 18.5

Ref

   

  > 18.5

1.15 (0.71  ̶ 1.85)

  0.575

  

Sex

 Male

Ref

   

 Female

0.85 (0.54  ̶ 1.34)

 0.484

  

Age

0.99 (0.96  ̶ 1.02)

 0.473

  
  1. aEffect of baseline CT value on change in colony count at weeks 2, 4, 6 and 8 with reference to the baseline count
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BMC Infectious Diseases

ISSN: 1471-2334

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