Table 1 Baseline characteristics of cirrhotic patients with septic shock (n = 88)

Age, y, mean ± SD

56.3 ± 11.1

57.0 ± 12.1

55.4 ± 10.0

0.52

Male, n (%)

71 (80.7)

38 (80.9)

33 (80.5)

1.00

 Alcohol

47 (53.4)

27 (57.4)

20 (48.8)

0.52

 Viral Hepatitis

25 (28.4)

13 (27.7)

12 (29.3)

1.00

 Other

16 (18.1)

7 (14.9)

9 (22.0)

0.42

Child-Pugh Score, mean ± SD

10 ± 2

11 ± 2

9 ± 2

< 0.001^*

MELD score, mean ± SD

27 ± 7

30 ± 5

24 ± 7

< 0.001^*

SIRS, n (%)

66 (75.0)

37 (78.7)

29 (70.7)

0.46

qSOFA score ≥ 2, n (%)

27 (30.7)

18 (38.3)

9 (22.0)

0.11

ACLF, n (%)

45 (51.1)

32 (68.1)

13 (31.7)

< 0.01^*

CLIF-SOFA score, mean ± SD

11 ± 3

13 ± 3

9 ± 3

< 0.001^*

 Diabetes Mellitus

26 (29.5)

12 (25.5)

14 (34.1)

0.48

 Hypertension

20 (22.7)

12 (25.5)

8 (19.5)

0.61

 Malignancy

24 (27.3)

13 (27.7)

11 (26.8)

1.00

 Cerebrovascular accident

11 (12.5)

5 (10.6)

6 (14.6)

0.75

 Obstructive lung disease

20 (22.7)

9 (19.1)

11 (26.8)

0.45

 Hemoglobin, g/dL, mean ± SD

10.3 ± 2.5

10.4 ± 2.4

10.1 ± 2.6

0.47

 Leukocyte, × 10⁹/L, median (IQR)

9.7 (4.7–15.5)

12.5 (5.8–16.1)

7.4 (3.7–13.4)

0.06

 Platelet, ×10⁹/L, median (IQR)

72.5 (45.3–121.3)

68 (45.0–116.0)

76 (44.5–130.5)

0.47

 INR, median (IQR)

1.6 (1.3–2.0)

1.7 (1.5–2.1)

1.4 (1.2–1.8)

< 0.01^*

 Bilirubin, mg/dL, median (IQR)

5.2 (2.4–12.0)

6.3 (3.2–15.4)

3.7 (2.0–7.9)

0.03^*

 Sodium, mmol/L, mean ± SD

131 ± 8

131 ± 9

131 ± 6

0.86

 Lactate, mmol/L, median (IQR)

4.0 (2.3–8.8)

6.3 (3.4–11.2)

2.7 (2.1–4.0)

< 0.01^*

 Creatinine, mg/dL, median (IQR)

2.1 (1.4–2.8)

2.2 (1.5–3.3)

1.6 (1.2–2.3).

0.40