Silent existence of eosinopenia in sepsis: a systematic review and meta-analysis

BMC Infectious Diseases

Table 1 The characteristics of included studies

Author	Year	Country	Study design	Clinical Setting	Reference standard	Severity of sepsis	Sample Size	Prevalence	Male	Mean/median Age	Control Patients	Cutoff (Cells/mm^3)	Timing of Eosinophils counts assessment
Abidi [15]	2008	Morocco	Prospective	ICU	ACCP/SCCM¹	Sepsis; severe sepsis; septic shock	177	120/177	101/177	42	SIRS + Negative	50	Admission
Abidi [15]	2008	Morocco	Prospective	ICU	ACCP/SCCM¹	Sepsis; severe sepsis; septic shock	177	120/177	101/177	42	SIRS	40	Admission
Anand [17]	2016	India	Prospective	ICU	ACCP/SCCM	severe sepsis	170	125/170	107/170	52	SIRS	50	Admission
Garnacho [18]	2014	Spain	Prospective	ICU	ACCP/SCCM	severe sepsis; septic shock	160	117/160	79/160	63	SIRS	25	Day1
Garnacho [18]	2014	Spain	Prospective	ICU	ACCP/SCCM	severe sepsis; septic shock	160	117/160	79/160	63	SIRS	25	Day2
Moura [21]	2011	Brazil	Retrospective	ICU	ACCP/SCCM	Sepsis; severe sepsis; septic shock	282	99/282		58.6 + −20	SIRS + Negative	100	Admission
Lavoignet [19]	2016	France	Retrospective	ED	ACCP/SCCM	Sepsis; severe sepsis; septic shock	692	125/692	0.45	59 + − 17.2	Non-infection	100	Continuous testing in one-week duration
												50
												10
López [20]	2010	Spain	Retrospective	ICU	ACCP/SCCM	Sepsis; severe sepsis; septic shock	244	55/244	165/244	54.4 + − 19.8	Non-infection	10	Day1
												50	Day1
												40	Day5
Shaaban [16]	2010	USA	Prospective	ICU	ACCP/SCCM	Sepsis; severe sepsis; septic shock	68	31/68	33/68	68	SIRS + noSIRS	50	Admission

Footnotes: ACCP/SCCM¹ American College of Chest Physicians/Society of Critical Care Medicine; Negative: negative results of bacterial culture, SIRS systemic inflammatory response syndrome, ICU intensive care unit

ISSN: 1471-2334