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Table 1 Characterization of the study population; 297 patients with positive PCR for Pneumocystis jirovecii

From: Epidemiological and clinical characteristics of immunocompromised patients infected with Pneumocystis jirovecii in a twelve-year retrospective study from Norway

Male sex, n (%) 180 (60.6)
Ever smoking, n (%) 162 (54.5)
Age (years), median, (q1-q3) 66 (59–74)
Immunosuppressive conditions, n (%)
Hematological malignancies 107 (36.0)
  Non-Hodgkin’s lymphoma 55 (18.5)
  Chronic leukemia 17 (5.7)
  Plasma cell disease 15 (5.1)
  Acute leukemia 11 (3.7)
  Hodgkin’s lymphoma 9 (3.0)
Solid tumors 75 (25.3)
  Lung including pleural membranes 27 (9.1)
  Breast 14 (4.7)
  Genitourinary tract 14 (4.7)
  Gastrointestinal tract 9 (3.0)
  Other primary tumora 11 (3.7)
Immunological disorders 46 (15.5)
  Rheumatoid arthritis 16 (5.4)
  Connective tissue disorders and vasculitidies 15 (5.1)
  Miscellaneousb disorders 15 (5.1)
Solid organ transplantations 37 (12.5)
  Kidney 31 (10.4)
  Heart, lung 6 (2.0)
Chronic lung diseases 18 (6.1)
  Interstitial lung disease or sarcoidosis 11 (3.7)
  Chronic obstructive pulmonary disease 7 (2.4)
HIV-infection 7 (2.4)
Otherc 7 (2.4)
Comorbid conditions, n (%)
 Hypertension 92 (31.0)
 Cardiovascular disease 83 (27.9)
 Chronic pulmonary disease 52 (17.5)
 Diabetes mellitus type 1 or 2 44 (14.8)
 Solid tumor 30 (10.1)
 Chronic kidney disease 38 (12.8)
 Congestive heart failure 18 (6.1)
 Rheumatic disease 12 (4.0)
 Hematological malignancyd 13 (4.4)
 Chronic liver disease 4 (1.4)
Charlson comorbidity index, n (%)
  < 4 47 (15.8)
 4–6 132 (44.4)
  > 6 118 (39.7)
  1. Abbreviations: AIHA autoimmune hemolytic anemia, ITP immune thrombocytopenic purpura, PCR polymerase chain reaction
  2. aOther primary tumors include brain tumors (i.e., astroglioma, meningioma), nasopharyngeal carcinoma, melanoma, adrenal gland tumor, sarcoma, and mesothelioma
  3. bMiscellaneous immunological disorders include hematological disorders (ITP, AIHA), skin disorders, uveitis, inflammatory diseases of gastrointestinal tract and arthritidies other than rheumatoid arthritis
  4. cOther immunosuppressive conditions include one patient with statin-induced myositis, one patient with common variable immunodeficiency and four patients with no established disorder at the time of presentation
  5. dIn 13 patients, hematological malignancy was not considered the primary immunosuppressive condition nor indication for immunosuppression but rather comorbidity