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Table 2 Changes in CSF cytokine levels during therapy

From: A preliminary study on the characteristics of Th1/Th2 immune response in cerebrospinal fluid of AIDS patients with cryptococcal meningitis

Cytokine
(pg/ml)
Baseline
(n = 11)
Week 2
(n = 10)
Week 4
(n = 8)
IL-1β 0.10 (0.04,0.98) 0.07 (0.04,0.17) 0.11 (0.04,0.16)
IL-2 0.16 (0.11,0.34) 0.13 (0.12,0.16) 0.14 (0.13,0.23)
IL-4 0.09 (0.07,0.13) 0.09 (0.06,0.14) 0.09 (0.07,0.11)
IL-5 0.90 (0.58,2.73) 1.16 (0.73,1.42) 2.74 (1.00,3.48)
IL-6 43.8 (8.32,162) 7.43 (3.89,17.4) 27.8 (2.98,62.2)
IL-7 0.05 (0.02,0.15) 0.05 (0.03,0.06) 0.07 (0.03,0.09)
IL-10 2.56 (1.22,21.7) 2.19 (1.33,3.87) 2.26 (1.48,4.11)
IL-12(p40) 3.52 (2.89,4.37) 2.89 (1.92,6.58) 3.14 (2.13,5.47)
IL-13 1.50 (1.22,2.89) 1.33 (1.11,1.56) 1.40 (1.24,2.35)
IL-15 4.94 (2.19,7.69) 4.54 (2.81,7.87) 6.30 (2.84,11.2)
IL-17A 0.70 (0.44,0.83) 0.38 (0.33,0.54) 0.48 (0.31,0.77)
IL-18 1.63 (1.04,4.91) 2.40 (1.02,8.97) 2.69 (1.07,11.9)
IFN-γ 0.64 (0.39,5.32) 0.43 (0.32,0.73) 0.46 (0.36,2.59)
TNF-α 20.6 (2.26,36.3) 4.58 (3.11,19.5) 5.81 (4.43,21.2)
IL-8 36.7 (9.44,431) 24.2 (22.8,73.8) 39.7 (21.4,147)
CXCL10 102 (4.16,791) 315 (27.6,780) 261 (24.0,1707)
CCL2 1209 (629,5751) 1079 (851,4060) 2578 (846,5136)
CCL3 0.26 (0.09,12.9) 0.24 (0.08,4.68) 0.32 (0.12,1.08)
VEGF-A 0.52 (0.44,0.55) 0.48 (0.38,0.49) 0.43 (0.29,0.46)
  1. IL Interleukin, IFN Interferon, TNF Tumor Necrosis Factor, VEGF-A Vascular Endothelial Growth Factor A. Data are presented as median [interquartile range, (IQR)]