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Table 1 Baseline characteristics of the three groups

From: A preliminary study on the characteristics of Th1/Th2 immune response in cerebrospinal fluid of AIDS patients with cryptococcal meningitis

Parameters HIV + CM+
(n = 12)
HIV + CM-
(n = 6)
HIV-CM-
(n = 17)
P value
Demographics
Age (years) 38.5 (34.5,46.5) 41.5 (34.0,54.3) 38.0 (28.5,49.5) 0.689
female, n (%) 2 (17) 1 (17) 12 (71) 0.005
Laboratory exam
WBC count(×10^9/L) 5.4 (3.4,9.0) 4.8 (2.4,6.2) 5.6 (4.5,6.5) 0.543
Lymphocyte count (×10^9/L) 0.5 (0.3,0.7) 0.8 (0.6,1.1) 2.0 (1.3,2.1) < 0.001
Hemoglobin (HGB) (g/L) 115 (76,133) 124 (112,126) 136 (130,144) 0.003
Platelet count (×10^9/L) 179 (116,247) 214 (202,264) 241 (170,279) 0.187
ALT (U/L) 31 (19,43) 21 (13,30) 20 (15,22) 0.070
TBIL (μmol/L) 9.7 (7.0,16.2) 7.4 (3.9,9.6) 9.8 (6.1,11.4) 0.206
Albumin (g/L) 32.1 (28.8,36.4) 31.1 (28.9,33.0) 42.2 (38.6,46.3) < 0.001
Creatinine (μmol/L) 57.9 (51.2,66.8) 59.0 (43.5,68.3) 58.0 (49.0,65.7) 0.756
Serum potassium (mmol/L) 4.0 (3.3,4.6) 4.0 (3.7,4.3) 4.0 (3.9,4.1) 0.958
Serum sodium (mmol/L) 135 (130,138) 138 (136,140) 139 (138,141) 0.019
Serum chloride (mmol/L) 102 (99,105) 102 (98,105) 105 (104,106) 0.025
CD4+T-cell count (cells/μl) 21 (8,36) 27 (10,61) 702 (515,878) < 0.001
HIV load (log10 copies/ml) 4.5 (4.1,4.8) 4.9 (4.2,5.3) 0.223
CSF parameters
ICP (mmH2O) 220 (98,310) 90 (75,135) 110 (95,128) 0.036
WBC count (×10^6/L) 21.5 (3.3,91.8) 1.5 (1.0,2.0) 2.0 (1.0,3.0) 0.002
Lymphocyte count (× 10^6/L) 8.0 (1.8,35.3) 1.0 (0.0,2.0) 1.0 (1.0,2.0) 0.001
Glucose (mmol/L) 2.3 (1.7,3.3) 3.1 (2.8,3.8) 3.0 (2.9,3.3) 0.060
Chlorine (mmol/L) 122 (119,123) 123 (120,128) 125 (124,127) 0.010
Total protein (mg/L) 271.6 (112.0,355.1) 172.3 (144.3,225.6) 145.4 (114.5,182.0) 0.111
  1. HIV human immunodeficiency virus, CM cryptococcal meningitis, WBC white blood cell, ALT alanine aminotransferase, TBIL total bilirubin, CSF cerebrospinal fluid, ICP intracranial pressure. Data are presented as median [interquartile range, (IQR)] or cases (percentage)