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Table 1 Comparison of clinical characteristics and laboratory findings between EV-positive patients and EV-negative patients from 2018 to 2019

From: Analysis of enterovirus genotypes in the cerebrospinal fluid of children associated with aseptic meningitis in Liaocheng, China, from 2018 to 2019

Characterics EV-positive patients
(n = 107)
EV-negative patients
(n = 397)
P value
Agea (years) 6.6 ± 3.1 5.6 ± 3.1 0.019
Male [no. (%)] 71(66.4) 258(65) 0.792
Hospital staya (days) 9.3 ± 2.3 9.2 ± 2.2 0.902
Fever duration before admissiona (days) 2.3 ± 2.4 2.9 ± 2.8 0.059
Clinical symptoms and signs [no. (%)]
 Fever 101(94.4) 366(92.2) 0.438
 Headache 98(91.6) 304(76.6) 0.001
 Vomiting 47(44) 185(46.6) 0.622
 Lethargy 44(41.1) 129(32.5) 0.095
 dizzy 56(52.3) 148(37.3) 0.005
 Convulsion 1(0.9) 28(7.1) 0.016
 Neck stiffness 19(17.8) 30(7.6) 0.002
 Anterior fontanelle bulge 0(0) 4(1) 0.297
 Babinski’s sign and/or Brudzinski’s sign 19(17.8) 116(29.2) 0.017
 Respiratory symptomsb 78(72.9) 239(60.2) 0.017
CSF findings [no. (%)]
 White blood cell > 10 × 106/L 99(92.5) 275(69.3) < 0.001
 Protein > 40 mg/dL 21(19.6) 37(9.3) 0.003
  1. a mean ± SD
  2. b Respiratory symptoms include coarse breath sounds, cough and other symptoms