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Table 1 Comparison of clinical characteristics and laboratory findings between EV-positive patients and EV-negative patients from 2018 to 2019

From: Analysis of enterovirus genotypes in the cerebrospinal fluid of children associated with aseptic meningitis in Liaocheng, China, from 2018 to 2019

Characterics

EV-positive patients

(n = 107)

EV-negative patients

(n = 397)

P value

Agea (years)

6.6 ± 3.1

5.6 ± 3.1

0.019

Male [no. (%)]

71(66.4)

258(65)

0.792

Hospital staya (days)

9.3 ± 2.3

9.2 ± 2.2

0.902

Fever duration before admissiona (days)

2.3 ± 2.4

2.9 ± 2.8

0.059

Clinical symptoms and signs [no. (%)]

 Fever

101(94.4)

366(92.2)

0.438

 Headache

98(91.6)

304(76.6)

0.001

 Vomiting

47(44)

185(46.6)

0.622

 Lethargy

44(41.1)

129(32.5)

0.095

 dizzy

56(52.3)

148(37.3)

0.005

 Convulsion

1(0.9)

28(7.1)

0.016

 Neck stiffness

19(17.8)

30(7.6)

0.002

 Anterior fontanelle bulge

0(0)

4(1)

0.297

 Babinski’s sign and/or Brudzinski’s sign

19(17.8)

116(29.2)

0.017

 Respiratory symptomsb

78(72.9)

239(60.2)

0.017

CSF findings [no. (%)]

 White blood cell > 10 × 106/L

99(92.5)

275(69.3)

< 0.001

 Protein > 40 mg/dL

21(19.6)

37(9.3)

0.003

  1. a mean ± SD
  2. b Respiratory symptoms include coarse breath sounds, cough and other symptoms