Table 3 Disease detection, colposcopies needed, and false positive (negative) rates of different triage strategies (N = 2731)
Triage strategies | Number of colposcopies | CRR (%) | Number of CIN2+/ CIN3+ detected | NRND for CIN2+/CIN3+ | FPR (%) for CIN2+ | FNR (%) for CIN2+ |
|---|---|---|---|---|---|---|
Single test | ||||||
 1.p16+ | 698 | 25.6 | 113/42 | 6.2/16.6 | 22.5 | 16.9 |
 2.HPV16+ | 624 | 22.8 | 85/46 | 7.3/13.6 | 20.8 | 37.5 |
 3.HPV16/33+ | 756 | 27.7 | 92/48 | 8.2/15.8 | 25.6 | 32.4 |
 4.HPV16/33/58+ | 1094 | 40.1 | 106/50 | 10.3/21.9 | 38.1 | 22.1 |
 5.HPV16/33/58/31+ | 1240 | 45.4 | 111/50 | 11.2/24.8 | 43.5 | 18.4 |
 6.HPV16/33/58/31/35+ | 1301 | 47.6 | 113/50 | 11.5/26.0 | 45.8 | 16.9 |
 7.HPV16/18 + (comparator) | 888 | 32.5 | 93/49 | 9.5/18.1 | 30.6 | 31.6 |
 8.HPV16/18/31/33/45/52/58+ | 1885 | 69.0 | 125/52 | 15.1/36.3 | 67.8 | 8.1 |
HPV types + or p16+ | ||||||
 9.HPV16+ or p16+ | 1049 | 38.4 | 127/52 | 8.3/20.2 | 35.5 | 6.6 |
 10.HPV16/33+ or p16+ | 1150 | 42.1 | 128/52 | 9.0/22.1 | 39.4 | 5.9 |
 11.HPV16/33/58+ or p16+ | 1406 | 51.5 | 132/53 | 10.7/26.5 | 49.1 | 2.9 |
 12.HPV16/33/58/31+ or p16+ | 1522 | 55.7 | 132/53 | 11.5/28.7 | 53.6 | 2.9 |
 13.HPV16/33/58/31/35+ or p16+ | 1570 | 57.5 | 132/53 | 11.9/29.6 | 55.4 | 2.9 |
 14.HPV16/18+ or p16+ | 1219 | 44.6 | 129/53 | 9.4/23.0 | 42.0 | 5.1 |
 15.HPV16/18/31/33/45/52/58+ or p16+ | 2007 | 73.5 | 133/53 | 15.1/37.9 | 72.2 | 2.2 |
HPV types + & p16+ | ||||||
 16.HPV16+ or HPV33/58/31/35 + &p16+ | 780 | 28.6 | 108/49 | 7.2/15.9 | 25.9 | 20.6 |
 17.HPV16/33+ or HPV58/31/35 + &p16+ | 881 | 32.3 | 109/49 | 8.1/18.0 | 29.7 | 19.9 |
 18.HPV16/33/58/31/35 + &p16+ | 429 | 15.7 | 94/39 | 4.6/11.0 | 12.9 | 30.9 |
 19.HPV16/18/31/33/45/52/58 + &p16+ | 576 | 21.1 | 105/41 | 5.5/14.0 | 18.2 | 22.8 |