Developing and validating a risk algorithm to diagnose Neisseria gonorrhoeae and Chlamydia trachomatis in symptomatic Rwandan women

Table 4 Risk algorithm performance to identify NG or CT infection in symptomatic women compared with Rwandan National Criteria

	Sensitivity	Specificity	PPV	NPV
Risk Score
Derivation cohort
Score > =4	91%	36%	43%	88%
Score > =5	81%	54%	48%	85%
Score > =6	65%	74%	57%	80%
Score > =7	44%	84%	59%	74%
External validation cohort
Score > =4	79%	33%	32%	80%
Score > =5	67%	48%	34%	79%
Score > =6	53%	66%	38%	78%
Score > =7	35%	79%	39%	76%
Rwanda National Criteria
Derivation cohort
Score > =2^a	26%	89%	55%	69%

CT Chlamydia trachomatis, NG Neisseria gonorrhoeae, PPV positive predictive value, NPV negative predictive value
^aCurrent cutoff used in the 2019 Rwandan National Guidelines

ISSN: 1471-2334