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Table 4 Risk algorithm performance to identify NG or CT infection in symptomatic women compared with Rwandan National Criteria

From: Developing and validating a risk algorithm to diagnose Neisseria gonorrhoeae and Chlamydia trachomatis in symptomatic Rwandan women

  Sensitivity Specificity PPV NPV
Risk Score
Derivation cohort
  Score > =4 91% 36% 43% 88%
  Score > =5 81% 54% 48% 85%
  Score > =6 65% 74% 57% 80%
  Score > =7 44% 84% 59% 74%
External validation cohort
  Score > =4 79% 33% 32% 80%
  Score > =5 67% 48% 34% 79%
  Score > =6 53% 66% 38% 78%
  Score > =7 35% 79% 39% 76%
Rwanda National Criteria
Derivation cohort
  Score > =2a 26% 89% 55% 69%
  1. CT Chlamydia trachomatis, NG Neisseria gonorrhoeae, PPV positive predictive value, NPV negative predictive value
  2. aCurrent cutoff used in the 2019 Rwandan National Guidelines