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Table 4 Risk algorithm performance to identify NG or CT infection in symptomatic women compared with Rwandan National Criteria

From: Developing and validating a risk algorithm to diagnose Neisseria gonorrhoeae and Chlamydia trachomatis in symptomatic Rwandan women

 

Sensitivity

Specificity

PPV

NPV

Risk Score

 Derivation cohort

  Score > =4

91%

36%

43%

88%

  Score > =5

81%

54%

48%

85%

  Score > =6

65%

74%

57%

80%

  Score > =7

44%

84%

59%

74%

 External validation cohort

  Score > =4

79%

33%

32%

80%

  Score > =5

67%

48%

34%

79%

  Score > =6

53%

66%

38%

78%

  Score > =7

35%

79%

39%

76%

Rwanda National Criteria

 Derivation cohort

  Score > =2a

26%

89%

55%

69%

  1. CT Chlamydia trachomatis, NG Neisseria gonorrhoeae, PPV positive predictive value, NPV negative predictive value
  2. aCurrent cutoff used in the 2019 Rwandan National Guidelines