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Table 3 Complications, Treatment and Outcome in pediatric patients infected with Covid-19, Influenza A and Influenza B

From: Comparative study of hospitalized children with acute respiratory distress syndrome caused by SARS-CoV-2 and influenza virus

  Covid-19
(N = 248)
A influenza
(N = 188)
B influenza
(N = 149)
P Value
Treatment
 Antiviral therapy 50 (20.16%) 86 (45.74%) 65 (43.62%) < 0.0001
 Antibiotic therapy 109 (43.95%) 166 (88.30%) 143 (95.97%) < 0.0001
 Use of corticosteroid 3 (1.21%) 23 (12.23%) 13 (8.72%) 0.0001
 Interferon α 235 (94.76%) 22 (11.70%) 13 (8.72) < 0.0001
 Immunoglobulin 1 (0.40%) 4((2.13%) 5 (3.36%) 0.0774
 ICU 4 (1.61%) 14 (7.45%) 4 (2.68%) 0.0043
Oxygen support
 Nasal cannula 3 (1.21%) 28 (14.89%) 15 (10.07%) < 0.0001
 Invasive mechanical ventilation 4 (1.61%) 6 (3.19%) 2 (1.34%) 0.4164
Complications
 Cardiac injury 18 (7.26%) 37 (19.68%) 27 (18.12%) 0.0002
 Liver dysfunction 13 (5.24%) 7 (3.72%) 3 (2.01%) 0.2725
 Acute gastroenteritis 5 (2.02%) 5 (2.66%) 1 (0.67%) 0.4017
 Neutropenia 0 8 (4.26%) 9 (6.04%) 0.0010
 Lung injury 0 6 (3.19%) 0 0.0017
 Renal injury 2 (0.81%) 1 (0.53%) 0 0.5520
 MODS 2 (0.81%) 2 (1.06%) 0 0.4769
Clinical outcome
 Discharge or in hospital 247 188 149  
 Death 1 0 0