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Table 3 Hematological and blood biochemical measurements of the 71 age-matched pediatric IA and COVID-19 patient pairs: abnormally high or lowa

From: Comparison of clinical features on admission between coronavirus disease 2019 and influenza a among children: a retrospective study in China

  IyesCyes IyesCno InoCyes InoCno P OR (95% CI)
Blood routine (n = 59)
 Lymphocytes
  Count abnormally low 5 (8.5) 22 (37.3) 4 (6.8) 28 (47.5) < 0.01 5.50 (1.90–16.0)
  Percentage abnormally low 3 (5.1) 19 (32.2) 2 (3.4) 35 (59.3) < 0.01 9.50 (2.21–40.8)
Neutrophils
  Count abnormally low 4 (6.8) 2 (3.4) 19 (32.2) 34 (57.6) < 0.01 0.11 (0.02–0.45)
  Percentage abnormally low 0 (0) 0 (0) 6 (10.2) 53 (89.8) 0.03 0.00 (0.00–0.85)
 Hemoglobin
  Abnormally low 4 (6.8) 13 (22.0) 2 (3.4) 40 (67.8) < 0.01 6.50 (1.47–28.8)
Coagulation function (n = 51)
 APPT (s) †
  Abnormally high 2 (3.9) 18 (35.3) 0 (0) 31 (60.8) < 0.01
 PT (s) †
  Abnormally high 0 (0) 13 (25.5) 0 (0) 38 (74.5) < 0.01
Blood biochemistry
 C-reactive protein (n = 61)
  Abnormally high 5 (8.2) 24 (39.3) 7 (11.5) 25 (41.0) < 0.01 3.43 (1.48–7.96)
 Procalcitonin (n = 44)
  Abnormally high 10 (22.7) 28 (63.6) 3 (6.8) 3 (6.8) < 0.01 9.33 (2.84–30.7)
  1. aFor each measurement, the exact number of patient pairs included into the analysis varied due to missing values. Data are presented in count and percentage (in parentheses). The P values were calculated using McNemar’s χ2 test. The I and C combinations denote whether a particular measurement was abnormally high/low (subscript yes) or not (subscript no) for an IA (I) and COVID-19 (C) patient pair. †OR was not calculable due to the zero value for the InoCyes combination
  2. Abbreviations: APTT activated partial thromboplastin time, COVID-19 coronavirus disease 19, CI confidence interval, IA influenza A, OR odds ratio, PT prothrombin time