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Table 5 Adverse drug reactions of artemisinin combination therapies among P. falciparum patients (9 studies included)

From: Efficacy and safety of artemisinin-based combination therapies for the treatment of uncomplicated malaria in pediatrics: a systematic review and meta-analysis

No.

Drug used in the study

Number of studies mentioned ADRs as drug related

Frequency (%) of patients with ADRs relevant to specific treatment regimen

1

Artemether–Lumefantrine (AL)

5

88/1263 (6.9%)

2

Artesunate–Amodiaquine (AS+AQ)

5

69/1574 (4.4%)

3

Dihydroartemisinin–Piperaquine (DP)

2

5/273 (1.8%)

4

Artesunate-Sulphamethoxypyrazine-Pyrimethamine (AS+SMP)

1

3/250 (1.2%)

5

Pyronaridine:artesunate (PA) (tab & granule)

1

7/30 (23.3%)

6

Chlorproguanil-dapsone-artesunate (CDA)

1

184/914 (20.1%)

 

Total

 

356/4304 (8.3%)