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Table 2 Univariate and multivariate analyses showing significant predictive factors of acute kidney injury (n = 1252)

From: Impact of acute kidney injury on survival in patients with chronic hepatitis C: a retrospective cohort study

Variable Univariate analysis Multivariate analysis
P HR (95% CI) P HR (95% CI)
Male 0.022 1.32 (1.04–1.68) 0.057 1.28 (0.99–1.64)
Age per year < 0.001 1.03 (1.02–1.04) 0.041 1.01 (1.00–1.02)
Hypertension < 0.001 1.58 (1.24–2.00) 0.003 1.49 (1.14–1.94)
Diabetes < 0.001 1.97 (1.55–2.51) 0.041 1.31 (1.01–1.69)
Platelet per 109/L < 0.001 0.99 (0.99–1.00) 0.348 0.99 (0.99–1.01)
MELD score per point < 0.001 1.15 (1.13–1.18) 0.035 1.06 (1.00–1.11)
Child-Pugh score per point < 0.001 1.72 (1.59–1.86) < 0.001 1.26 (1.09–1.46)
SVR < 0.001 0.21 (0.16–0.29) < 0.001 0.31 (0.23–0.43)
Extrahepatic malignancy 0.002 1.73 (1.22–2.47) 0.009 1.65 (1.13–2.41)
CH (diagnosis at entry) Reference Reference
 Com-LC 0.001 1.83 (1.26–2.65) 0.102 1.40 (0.94–2.09)
 Decom-LC or HCC < 0.001 5.49 (4.10–7.35) < 0.001 2.47 (1.72–3.57)
  1. Abbreviations: HR Hazard ratio, CI Confidence interval, MELD score Model for end-stage liver disease score, SVR Sustained virologic response, Com-LC Compensated cirrhosis, Decom-LC Decompensated cirrhosis, HCC Hepatocellular carcinoma
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