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Table 3 Effects of TCHMs on lipid profiles of follow-up COVID-19 patients

From: Follow-up study on serum cholesterol profiles and potential sequelae in recovered COVID-19 patients

Laboratory values (mg/dL) COVID-19 follow-up patients
Mild group (59) Severe/Critical group (48)
Non-TCHM (25) TCHM (34) Non-TCHM (31) TCHM (17)
Adm Flw p Adm Flw p Adm Flw p Adm Flw p
No cholesterol-lowering drugs (n) N = 17 N = 33 N = 24 N = 17
LDL-c 97.8 (90.3, 113.5) 103.5 (89.6, 115.9) 0.211 101.3 (84.6, 113.3) 101.7 (87.0, 120.3) 0.136 90.9 (74.3, 113.5) 102.1 (81.6, 124.1) 0.011 101.3 (79.1, 108.7) 112.9 (99.4, 129.7) 0.089
HDL-c 50.3 (44.1, 64.5) 51.3 (46.2, 65.9) 0.478 57.6 (49.5, 65.4) 57.2 (46.8, 65.0) 0.868 50.1 (41.3, 59.7) 57.0 (47.0, 66.6) 0.001 51.8 (46.2, 72.3) 51.0 (44.8, 61.7) 0.169
Non-HDL-c 138.6 (125.9, 171.5) 145.8 (126.0, 173.5) 0.198 144.2 (115.6, 158.9) 153.5 (124.9, 165.9) 0.040 122.0 (88.3, 168.7) 152.0 (118.3, 186.8) 0.015 139.2 (114.7, 154.5) 162.0 (144.2, 203.9) 0.058
With cholesterol-lowering drugs (n) N = 8 N = 1 N = 7 N = 0
32% 32%   3% 3% 0.003* 29% 29%   0 0 0.033*
  1. TCHMs traditional Chinese herbal medications, Adm admission, Flw follow-up, non-TCHM patients did not receive any traditional Chinese herbal medications, TCHM patients received any types of traditional Chinese herbal medications during the illness or / and recovery. Data are presented as median (IQR), n, or %. The p value is calculated using a Wilcoxon signed-rank test (two-sided) to compare variables at the times of admission with follow-up from the same subjects within subgroups. In both mild and severe groups, the lipid values at the time of admission or follow-up in the non-TCHM subgroup is compared with that in the TCHM subgroup using a Mann-Whitney U test; the p values are not shown since no statistical significance is found. *Fisher extract test is used. A total of 16 patients (n = 9 in mild and n = 7 in severe/critical cases) who had cholesterol-lowering drugs were excluded from the inter-subgroup analyses above