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Table 1 Comparison of clinical features between E. coli-EOD group and E. coli-LOD group

From: Epidemiology and antimicrobial susceptibility of invasive Escherichia coli infection in neonates from 2012 to 2019 in Xiamen, China

Characteristics

E. coli-EOD

(n = 46)

E. coli-LOD

(n = 48)

χ2/t/z value

P

Maternal

 Age, n (%)

   < 20 years

2 (4.35)

1 (2.08)

0.001

0.970

   ≥ 35 years

4 (8.70)

8 (16.67)

1.34

0.247

Regular antenatal screening, n (%)

38 (82.61)

41 (85.42)

0.138

0.710

Cesarean section, n (%)

20 (43.48)

14 (29.17)

2.081

0.155

Prenatal hormone usage, n (%)

4 (8.70)

14 (29.17)

5.362

0.020

PROM, n (%)

8 (17.39)

7 (14.58)

0.138

0.710

GDM, n (%)

17 (36.96)

4 (8.33)

11.091

0.001

Intrapartum temperature ≥ 37.5 °C, n (%)

24 (52.17)

1 (2.08)

30.189

0.000

Gestational vaginitis, n (%)

10 (21.74)

2 (4.17)

6.513

0.011

Gestational bacteriuria, n (%)

7 (15.22)

0 (0.00)

5.839

0.016

Chorioamnionitis, n (%)

28 (60.87)

9 (18.75)

17.459

0.000

Positive E. coli culture in placental swab or cervical secretions, n (%)

21 (45.65)

1 (2.08)

24.873

0.000

Neonatal

 Gender (case, male / female)

30/16

31/17

0.021

0.880

 Gestational age, median (IQR), weeks

39.8 (39,40.7)

37.1 (32.73,39.28)

4.253

0.000

 Preterm, n (%)

4 (8.70)

20 (41.67)

13.433

0.000

 Birth weight, median (IQR), grams

3400 (2983,3663)

2875 (1765,3375)

3.138

0.002

 Low birth weight, n (%)

4 (8.70)

17 (35.42)

9.667

0.002

 Small for gestational age, n (%)

0 (0.00)

2 (4.17)

0.495a

 Asphyxia, n (%)

3 (6.52)

6 (12.5)

0.402

0.526

 MSAF, n (%)

26 (56.52)

1 (2.08)

34.002

0.000

 Breast-feeding, n (%)

40 (86.96)

32 (66.67)

5.394

0.022

 Mechanical ventilation, n (%)

25 (54.35)

7 (14.58)

16.542

0.000

 Duration of mechanical ventilation, median (IQR), days

3.0 (1.5,4.5)

5.0 (3.0,10.0)

0.754

0.456

 Shortness of breath, n (%)

38 (82.61)

16 (33.33)

23.330

0.000

 Fever, n (%)

2 (4.35)

26 (54.17)

27.880

0.000

 Convulsions, n (%)

2 (4.35)

2 (4.17)

0.000

1.000

 Poor response, n (%)

3 (6.52)

3 (6.25)

0.000

1.000

 Jaundice, n (%)

0 (0.00)

1 (2.08)

1.000a

 Nosocomial infection, n (%)

0 (0.00)

18 (37.50)

21.340

0.000

 Duration of UVC, mean ± SD, days

4.00 ± 1.79

6.11 ± 3.14

1.483

0.162

 Duration of PICC, median (IQR), days

30.00 (10.50,67.00)

28.00 (17.00,52.50)

0.153

0.881

 Length of hospitalization, median (IQR), days

13.5 (8,16)

16 (14,30)

2.794

0.005

 Mortality, n (%)

3 (6.52)

2 (5.32)

0.002

0.961

  1. PROM premature rupture of membranes, GDM gestational diabetes mellitus, MSAF meconium-stained amniotic fluid, UVC umbilical vein catheterization, PICC peripherally inserted central catheter
  2. aFisher’s exact test