Skip to main content

Table 1 Comparison of clinical features between E. coli-EOD group and E. coli-LOD group

From: Epidemiology and antimicrobial susceptibility of invasive Escherichia coli infection in neonates from 2012 to 2019 in Xiamen, China

Characteristics E. coli-EOD
(n = 46)
E. coli-LOD
(n = 48)
χ2/t/z value P
Maternal
 Age, n (%)
   < 20 years 2 (4.35) 1 (2.08) 0.001 0.970
   ≥ 35 years 4 (8.70) 8 (16.67) 1.34 0.247
Regular antenatal screening, n (%) 38 (82.61) 41 (85.42) 0.138 0.710
Cesarean section, n (%) 20 (43.48) 14 (29.17) 2.081 0.155
Prenatal hormone usage, n (%) 4 (8.70) 14 (29.17) 5.362 0.020
PROM, n (%) 8 (17.39) 7 (14.58) 0.138 0.710
GDM, n (%) 17 (36.96) 4 (8.33) 11.091 0.001
Intrapartum temperature ≥ 37.5 °C, n (%) 24 (52.17) 1 (2.08) 30.189 0.000
Gestational vaginitis, n (%) 10 (21.74) 2 (4.17) 6.513 0.011
Gestational bacteriuria, n (%) 7 (15.22) 0 (0.00) 5.839 0.016
Chorioamnionitis, n (%) 28 (60.87) 9 (18.75) 17.459 0.000
Positive E. coli culture in placental swab or cervical secretions, n (%) 21 (45.65) 1 (2.08) 24.873 0.000
Neonatal
 Gender (case, male / female) 30/16 31/17 0.021 0.880
 Gestational age, median (IQR), weeks 39.8 (39,40.7) 37.1 (32.73,39.28) 4.253 0.000
 Preterm, n (%) 4 (8.70) 20 (41.67) 13.433 0.000
 Birth weight, median (IQR), grams 3400 (2983,3663) 2875 (1765,3375) 3.138 0.002
 Low birth weight, n (%) 4 (8.70) 17 (35.42) 9.667 0.002
 Small for gestational age, n (%) 0 (0.00) 2 (4.17) 0.495a
 Asphyxia, n (%) 3 (6.52) 6 (12.5) 0.402 0.526
 MSAF, n (%) 26 (56.52) 1 (2.08) 34.002 0.000
 Breast-feeding, n (%) 40 (86.96) 32 (66.67) 5.394 0.022
 Mechanical ventilation, n (%) 25 (54.35) 7 (14.58) 16.542 0.000
 Duration of mechanical ventilation, median (IQR), days 3.0 (1.5,4.5) 5.0 (3.0,10.0) 0.754 0.456
 Shortness of breath, n (%) 38 (82.61) 16 (33.33) 23.330 0.000
 Fever, n (%) 2 (4.35) 26 (54.17) 27.880 0.000
 Convulsions, n (%) 2 (4.35) 2 (4.17) 0.000 1.000
 Poor response, n (%) 3 (6.52) 3 (6.25) 0.000 1.000
 Jaundice, n (%) 0 (0.00) 1 (2.08) 1.000a
 Nosocomial infection, n (%) 0 (0.00) 18 (37.50) 21.340 0.000
 Duration of UVC, mean ± SD, days 4.00 ± 1.79 6.11 ± 3.14 1.483 0.162
 Duration of PICC, median (IQR), days 30.00 (10.50,67.00) 28.00 (17.00,52.50) 0.153 0.881
 Length of hospitalization, median (IQR), days 13.5 (8,16) 16 (14,30) 2.794 0.005
 Mortality, n (%) 3 (6.52) 2 (5.32) 0.002 0.961
  1. PROM premature rupture of membranes, GDM gestational diabetes mellitus, MSAF meconium-stained amniotic fluid, UVC umbilical vein catheterization, PICC peripherally inserted central catheter
  2. aFisher’s exact test