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Table 2 Diagnostic performance of the index and serial combined nasal and throat swab for the primary outcome of a diagnosis of confirmed or probable COVID-19

From: Diagnostic performance of the combined nasal and throat swab in patients admitted to hospital with suspected COVID-19

Serial tests True negative False negative True positive False positive Sensitivity
(95% CI)
Negative predictive value
(95% CI)
Positive predictive value
(95% CI)
Specificity
(95% CI)
1 (index test) 868 241 255 4 51.4 (48.8–54.1) 78.3 (76.0–80.4) 98.5 (97.7–99) 99.5 (99.0–99.8)
2 459 141 212 5 60.1 (56.7–63.4) 76.5 (73.5–79.3) 97.7 (96.4–98.5) 98.9 (98.0–99.4)
3 235 76 164 7 68.3 (64.0–72.3) 75.6 (71.5–79.2) 95.9 (93.7–97.3) 97.1 (95.2–98.3)
4 142 36 125 7 77.6 (72.7–81.9) 79.8 (75.0–83.9) 94.7 (91.6–96.7) 95.3 (92.3–97.2)
5 94 24 94 6 79.7 (73.8–84.5) 79.7 (73.8–84.5) 94.0 (90.0–96.5) 94.0 (90.0–96.5)
6 62 11 75 6 87.2 (81.0–91.6) 84.9 (78.4–89.7) 92.6 (87.3–95.8) 91.2 (85.6–94.7)
7 46 10 55 6 84.6 (77.0–90.0) 82.1 (74.2–88.0) 90.2 (83.4–94.3) 88.5 (81.4–93.1)
8 31 6 43 4 87.8 (79.1–93.2) 83.8 (74.5–90.2) 91.5 (83.6–95.8) 88.6 (80.0–93.7)
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