Phenotypic and genotypic drug sensitivity profiles of Mycobacterium tuberculosis infection and associated factors in northeastern Ethiopia

Table 3 Detection of isoniazid (katG, inhA and both katG and inhA) resistance by LPA with its resistance by MGIT testing method

LPA		MGIT isoniazid DST		Sensitivity	Specificity	Predictive value		Kappa
LPA		Resistant = 8	Sensitive = 57	Sensitivity	Specificity	Positive	Negative	Kappa
katG	Resistant	6	0	75	100	100	96.6	0.840 (P < 0.001)
katG	Sensitive	2	57	75	100	100	96.6	0.840 (P < 0.001)
inhA	Resistant	1	1	12.5	98.2	50	88.9	0.159 (P = 0.099)
inhA	Sensitive	7	56	12.5	98.2	50	88.9	0.159 (P = 0.099)
KatG and inhA	Resistant	1	0	12.5	100	100	89.1	0.2 (P = 0.007)
KatG and inhA	Sensitive	7	57	12.5	100	100	89.1	0.2 (P = 0.007)

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