Table 1 Clinical characteristics of patients from whom carbapenemase-producing Enterobacterales strains were isolated
Characteristics | All patients (n = 18) | Patients with isolation of ECC ST78 (n = 14) | Patients with isolation of ECC non-ST78 (n = 4) |
|---|---|---|---|
Age, mean y [SD] | 68.8 [8.1] | 69.1 [7.7] | 67.8 [9.0] |
 Age > 65y | 12 (66.7) | 9 (64.3) | 3 (75) |
Sex | |||
 Male | 16 (88.9) | 13 (92.9) | 3 (75) |
 Female | 2 (11.1) | 1 (7.1) | 1 (25) |
Status | |||
 Infection | 6 (33.3) | 5 (35.7) | 1 (25) |
 Colonization detected by clinical cultures | 7 (38.9) | 4 (28.6) | 3 (75) |
 Colonization detected by surveillance cultures | 5 (27.8) | 5 (35.7) | 0 (0) |
Sample from which CPE was first isolated | |||
 Sputum | 6 (33.3) | 5 (35.7) | 1 (25) |
 Bile | 3 (16.7) | 0 (0) | 3 (75) |
 Stool | 3 (16.7) | 3 (21.4) | 0 (0) |
 Intraabdominal fluid | 2 (11.1) | 2 (14.3) | 0 (0) |
 Other | 4 (22.2) | 4 (28.6) | 0 (0) |
Ward at the time of isolation of CPE | |||
 ICU | 6 (33.3) | 4 (28.6) | 2 (50) |
 Ward-V | 5 (27.8) | 5 (35.7) | 0 (0) |
 Ward-X | 3 (16.7) | 3 (21.4) | 0 (0) |
 Other | 4 (22.2) | 2 (14.3) | 2 (50) |
Department at the time of isolation of CPE | |||
 Surgery-A | 7 (38.9) | 5 (35.7) | 2 (50) |
 Surgery-B | 4 (22.2) | 4 (28.6) | 0 (0) |
 Medical Oncology-E | 3 (16.7) | 3 (21.4) | 0 (0) |
 Other | 4 (22.2) | 2 (14.3) | 2 (50) |
Type of malignancy | |||
 Gastrointestinal | 17 (94.4) | 14 (100) | 3 (75) |
 Thoracic | 1 (5.6) | 0 (0) | 1 (25) |
Cancer chemotherapy within 90 days | 6 (33.3) | 6 (42.9) | 0 (0) |
Antimicrobial use within 30 days | 16 (88.9) | 13 (92.9) | 3 (75) |
Surgery within 30 days | 14 (77.8) | 10 (71.4) | 4 (100) |
 Gastrointestinal | 13 (72.2) | 10 (71.4) | 3 (75) |
 Thoracic | 1 (5.6) | 0 (0) | 1 (25) |
Endoscopic procedure within 90 daysa | 15 (83.3) | 12 (85.7) | 3 (75) |
 Laryngoscopy | 3 (16.7) | 3 (21.4) | 0 (0) |
 Esophagogastroscopy | 13 (72.2) | 11 (78.6) | 2 (50) |
 Duodenoscopy with ERCP | 4 (22.2) | 2 (14.3) | 2 (50) |
 Colonoscopy | 6 (33.3) | 5 (35.7) | 1 (25) |
 Bronchoscopy | 2 (11.1) | 2 (14.3) | 0 (0) |
30-day mortality | 1 (5.6) | 1 (7.1) | 0 (0) |
90-day mortality | 3 (16.7) | 2 (14.3) | 1 (25) |