Table 3 Treatment details
From: Low-dose amikacin in the treatment of Multidrug-resistant Tuberculosis (MDR-TB)
Median (IQR) or Mean +/− SD | |
|---|---|
Median number of drugs in intensive phasea | 7 (6, 8) |
Median number of drugs in continuation phasea | 5 (4, 5) |
Median duration of amikacin treatment | |
Daily dosing (days) | 139 (92, 173) |
TIW dosing (days) | 115 (94, 150) |
Total duration (months) | 7.2 (5.7, 8) |
Median starting dose of amikacin (mg/kg) | |
Daily | 8.9 (8, 10) |
TIW | 8.1 (7.3, 9.2) |
Median cumulative dose of amikacin (g) | 80.6 (61.7, 100.4) |
Proportion of drug levels within target range | 89% (78–93%) |
Median number of audiometry tests during amikacin treatment | 3 (1, 5) |
Median total treatment duration (months) | 22 (20, 25) |