Table 1 Demographic and clinical characteristics of patients affected by the contaminated TPN outbreak in western Mexico
Characteristic | No. (% of patients)a | |||
|---|---|---|---|---|
Total | HC-FAA | HP-CMNO | HGZ-21 | |
No. of patients | 25 | 11 | 1 | 13 |
Mean age, months (range) | 78 (1–996) | 152 (1–996) | 4 | 21 (2–168) |
Male | 16 (64) | 5 (45.5) | 1 (100) | 10 (76.9) |
Hospital ward | ||||
Neonatal ICU | 19 (76) | 8 (72.7) | 1 (100) | 10 (76.9) |
Pediatric surgery | 4 (16) | 1 (9.1) | 0 (0) | 3 (23.1) |
General surgery | 1 (4) | 1 (9.1) | 0 (0) | 0 (0) |
Internal medicine | 1 (4) | 1 (9.1) | 0 (0) | 0 (0) |
Previous hospitalization | 8 (32) | 2 (18.2) | 0 (0) | 6 (46.1) |
Mean LOS (days) | 53.8 (15–252) | 49.1 (15–135) | 32 | 59.4 (30–252) |
Mean LOS to prior positive culture (days) | 22.5 (1–249) | 10.4 (1–22) | 14 | 33.5 (1–249) |
Mean LOS after positive culture (days) | 31.2 (3–135) | 39.6 (5–135) | 18 | 25.1 (3–31) |
UCI stay | 20 (80) | 7 (63.6) | 1 (100) | 12 (92.3) |
Previous surgery | 10 (40) | 1 (9.1) | 0 (0) | 9 (69.2) |
Number of antibiotics used before positive culture | ||||
1–3 | 15 (60) | 6 (54.5) | 1 (100) | 8 (61.5) |
4 or more | 10 (40) | 5 (45.5) | 0 (0) | 5 (38.5) |
Antibiotics used before positive culture, n (%) | ||||
Carbapenems | 18 (72) | 5 (45.5) | 0 (0) | 13 (100) |
Cephalosporins | 15 (60) | 11 (100) | 1 (100) | 3 (23.1) |
Aminoglycoside | 13 (52) | 8 (72.7) | 1 (100) | 4 (30.8) |
Glycopeptide | 7 (28) | 3 (27.3) | 0 (0) | 4 (30.8) |
Fluoroquinolones | 6 (24) | 0 (0) | 0 (0) | 6 (46.1) |
Penicillin | 5 (20) | 4 (36.4) | 0 (0) | 1 (7.7) |
Colistin | 4 (16) | 1 (9.1) | 0 (0) | 3 (23.1) |
Metronidazole | 3 (12) | 2 (18.2) | 0 (0) | 1 (7.7) |
Other | 7 (28) | 1 (9.1) | 0 (0) | 6 (46.1) |
Mortality | 1 (4) | 1 (9.1) | 0 (0) | 0 (0) |