From: Adenovirus viremia may predict adenovirus pneumonia severity in immunocompetent children
Characteristics | Severe Group (n = 60) | Mild Group (n = 51) | P Value |
---|---|---|---|
Demographics | |||
Male, n (%) | 32 (53%) | 32 (63%) | 0.317 |
Age, months (IQR) | 35 (21–50) | 48 (24–72) | 0.052 |
Clinical features, n (%) | |||
Bronchoscopy | 47 (78%) | 7 (14%) | – |
Plastic bronchitis | 12 (20%) | 0 | – |
ICU admission | 5 (8%) | 0 | – |
Laboratory tests | |||
WBC count, 109/L (IQR) | 12.86 (8.10–16.77) | 10 .30 (7.10–14.14) | 0.034 |
CRP, mg/L (IQR) | 33.64 (12.23–68.98) | 26.20 (11.70–43.70) | 0.091 |
Co-infection, n (%) | 48 (80%) | 25 (49%) | 0.001 |
Fungal co-infection, n | 2 | 0 | |
Bacterial co-infection, n (%) | 4 (7%) | 4 (8%) | 1.000 |
RSV co-infection, n (%) | 4 (7%) | 2 (4%) | 0.829 |
Influenza virus co-infection, n (%) | 12 (20%) | 7 (14%) | 0.382 |
MP co-infection, n (%) | 42 (70%) | 18 (35%) | < 0.001 |
Viremia, n (%) | 30 (50%) | 12 (24%) | 0.004 |
Blood viral load, log10 copies/mL (IQR) | 1.385 (0–4.255) | 0 (0–0) | 0.001 |