Impact of 16S rDNA sequencing on clinical treatment decisions: a single center retrospective study

BMC Infectious Diseases

Table 1 Microbiological characteristics of the population

Sample’s culture		+	+	–	–	N/A	Total
Direct examination		+	–	+	–	N/A
16S PCR		+	+	+	+	–
Samples	Cardiac valve	7	7	19	47	93	173
	Abscess	2	8	2	17	42	71
	Bone sample	2	4	0	8	66	80
	Soft tissue	3	2	0	6	56	67^a
	Synovial fluid	2	9	2	11	154	178
	CSF	2	1	5	5	106	119
	Pleural fluid	1	0	1	3	22	27
	Sonication fluid	1	6	2	1	8	18
	Aqueous humour	0	2	1	2	52	57
	Other	0	0	0	0	16	16^b
Total		20	39	32	100	615	806

^a23 cerebral biopsies, 15 synovial biopsies, 13 lymph nodes, 3 bone marrows, 4 skin biopsies, 2 vascular biopsies, 1 bladder, 1 oesophageal, 1 hepatic, 1 muscular, 1 subcutaneous, 1 pericardial and 1 ventricular biopsy
^b12 EDTA blood, 2 pericardial fluids, 1 ascitic fluid and 1 peritoneal dialysate samples
Abbreviations: PCR polymerase chain reaction, CSF cerebrospinal fluid

ISSN: 1471-2334